Correction to: Clinical and demographic characteristics of primary progressive multiple sclerosis in Argentina: Argentinean registry cohort study (RelevarEM)

Abstract

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New epidemiological data of multiple sclerosis, the impact of psychopathological symptoms on the health-related quality of life of multiple sclerosis patients

“…We found the distribution of different the disease courses in our cohort to be 2.86% CIS, 7.14% PPMS, 24.29% SPMS, 65.71% RRMS while employing the novel phenotype-based classification [7] most of the cohort could be classified into RR/CIS phenotype (68.57%, 288 patients), progressive disease type was seen in 132 patients (31.43%). The distribution of the classical disease courses fell in line with recent data based on large registries from both low and high prevalence countries across Europe [82][83][84][85][86][87][88][89][90]. However, except for the Argentinian cohort, none of these studies have used the most recent McDonald criteria, furthermore not one of these studies have evaluated their population according to the novel phenotypic classification or have given data about the disease activity of their patients, they only supply information about the prevalence of MS and the distribution of the classical disease courses.…”

Bacillus Calmette–Guerin vaccination and multiple sclerosis: A population‐based birth cohort study in Quebec, Canada

“…We investigated whether the excess risk was concentrated in a specific birth cohort or in a subgroup of cases with later MS onset, assuming that some of the older ones might be PPMS. If the sociodemographic characteristics [4,7,8] and pathogenesis of RRMS differ from PPMS through two types of inflammation [10], we may hypothesize different associations with BCG vaccination. The main distinctive characteristics available to us for distinguishing between RRMS and PPMS patients among those who did not take DMTs is an expected older age at diagnosis in the latter subgroup and different sex ratios.…”

“…Multiple sclerosis (MS) is a chronic neurodegenerative disease with variable courses [1]. The disease begins with one of two distinct clinical forms, relapsing-remitting (RRMS, 85%-90% of cases) or primary progressive (PPMS, 10%-15%) [2][3][4].…”

“…RRMS and PPMS differ in terms of prodromal periods [6], sociodemographic characteristics [4,7,8], environmental risk factors, and genetic susceptibility [3,6,9]. RRMS and PPMS patients also exhibit different central nervous system inflammation characteristics [10].…”