Correction to: A pathway map of AXL receptor-mediated signaling network

Dagamajalu, Shobha; Rex, Devasahayam Arokia Balaya; Palollathil, Akhina; Shetty, Rohan; Bhat, Guruprasad; Cheung, Lydia W.T.; Prasad, T. S. Keshava

doi:10.1007/s12079-020-00583-2

Cited by 2 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Considering the importance of MSP/RON signaling in inflammation and cancer, we created a map of the MSP signaling pathway. We generated a signaling pathway map of MSP, similar to the previously published pathways related to cancer, including CAMKK2 (Najar et al 2021), Axl (Dagamajalu et al 2021), CKAP4 (Suchitha et al 2023) and DDR1 (Dagamajalu et al 2022). Using literature data, we compiled the downstream signaling events by the interaction between MSP and its receptor into a signaling pathway map.…”

Section: Introductionmentioning

confidence: 99%

A network map of macrophage-stimulating protein (MSP) signaling

Sanjeev

Dagamajalu

Shaji

et al. 2023

J. Cell Commun. Signal.

Self Cite

View full text Add to dashboard Cite

Macrophage-stimulating protein (MSP), a serum-derived growth factor belonging to the plasminogen-related kringle domain family, is mainly produced by the liver and released into the blood. MSP is the only known ligand for RON ("Recepteur d'Origine Nantais", also known as MST1R), which is a member of the receptor tyrosine kinase (RTK) family. MSP is associated with many pathological conditions, including cancer, inflammation, and fibrosis. Activation of the MSP/RON system regulates main downstream signaling pathways, including phosphatidylinositol 3-kinase/ AKT serine/threonine kinase/

show abstract

Section: Introductionmentioning

confidence: 99%

A network map of macrophage-stimulating protein (MSP) signaling

Sanjeev

Dagamajalu

Shaji

et al. 2023

J. Cell Commun. Signal.

Self Cite

View full text Add to dashboard Cite

show abstract

“…In this study, the molecular events that occur based on TROP‐2 over expression and upon activation by cleavage have been compiled from the available literature. We compiled all the TROP‐2 mediated molecular signaling events to develop a comprehensive signaling pathway map, similar to the previously published signaling pathways (Raju et al 2014; Abhinand et al 2016; Rex et al 2020; Dagamajalu et al 2021; Aravind et al 2022).…”

Section: Introductionmentioning

confidence: 99%

An assembly of TROP2-mediated signaling events

Upadhyay

Rex

Parate

et al. 2023

J. Cell Commun. Signal.

Self Cite

View full text Add to dashboard Cite

Trophoblast cell surface antigen 2 (TROP2) is a calcium-transducing transmembrane protein mainly involved in embryo development. The aberrant expression of TROP2 is observed in numerous cancers, including triple-negative breast cancer, gastric, colorectal, pancreatic, squamous cell carcinoma of the oral cavity, and prostate cancers. The main signaling pathways mediated by TROP2 are calcium signaling, PI3K/AKT, JAK/STAT, MAPKs, and β-catenin signaling. However, collective information about the TROP2-mediated signaling pathway is not available for visualization or analysis. In this study, we constructed a TROP2 signaling map with respect to its role in different cancers. The data curation was done manually by following the NetPath annotation criteria. The described map consists of different molecular events, including 8 activation/ inhibition, 16 enzyme catalysis, 19 gene regulations, 12 molecular associations, 39 induced-protein expressions, and 2 protein translocation. The data of the TROP2 pathway map is made freely accessible through the WikiPathways Database (https:// www. wikip athwa ys. org/ index. php/ Pathw ay: WP5300).

show abstract

Correction to: A pathway map of AXL receptor-mediated signaling network

Abstract: The original version of this article unfortunately contained a mistake.

Cited by 2 publications

References 0 publications

A network map of macrophage-stimulating protein (MSP) signaling

A network map of macrophage-stimulating protein (MSP) signaling

An assembly of TROP2-mediated signaling events

Contact Info

Product

Resources

About