2013
DOI: 10.1371/annotation/049f74d0-919f-483c-a488-4740ec0a5f4d
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Correction: Small-Molecule Quinolinol Inhibitor Identified Provides Protection against BoNT/A in Mice

Abstract: Botulinum neurotoxins (BoNTs), etiological agents of the life threatening neuroparalytic disease botulism, are the most toxic substances currently known. The potential for the use as bioweapon makes the development of small-molecule inhibitor against these deadly toxins is a top priority. Currently, there are no approved pharmacological treatments for BoNT intoxication. Although an effective vaccine/immunotherapy is available for immuno-prophylaxis but this cannot reverse the effects of toxin inside neurons. A… Show more

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