Correction: Prevalence Study and Genetic Typing of Bovine Viral Diarrhea Virus (BVDV) in Four Bovine Species in China

Deng, Mingliang; Ji, Sukun; Fei, Wentao; Raza, Sohail; He, Chenfei; Chen, Yingyu; Chen, Huanchun; Guo, Aizhen

doi:10.1371/journal.pone.0134777

Cited by 54 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…BVDV-1 I included subtypes 1a, 1b, 1c, 1d, 1e, and 1i, while BVDV-1 II included subtypes 1f, 1g, 1h, 1m, 1n, 1o, 1q and one unclassified subtype detected in Italy. The phylogenetic tree showed the same general topology and BVDV-1 subtype clustering presented in previous reports [ 4 – 6 ]. Notably, all genomes of the same subtype clustered together as expected, including the sequence with unclassified subtype detected in Italy.…”

supporting

confidence: 78%

“…The ORF encodes a polyprotein that is processed into 12 polypeptides [ 3 ]. The classification of BVDV-1 into 21 subtypes (a through u) is primarily based on phylogenetic analysis of partial N pro sequences, and the N pro tree topology is reflected in trees constructed using the complete genome sequences [ 4 – 6 ]. The current knowledge of the circulating subtypes is important for epidemiological information, development of appropriate diagnostic tools, and introduction of control programs [ 7 ].…”

mentioning

confidence: 99%

See 1 more Smart Citation

Insights into the origin and diversification of bovine viral diarrhea virus 1 subtypes

et al. 2021

View full text Add to dashboard Cite

In this study, we performed phylogenetic and evolutionary analysis on bovine viral diarrhea virus 1 (BVDV-1) sequences to investigate the origin and temporal diversification of different BVDV-1 subtypes. Dated phylogenies using the complete polyprotein sequence were reconstructed, and the time of the most recent common ancestor (tMRCA) was estimated. The results demonstrated that BVDV-1 subtypes clustered into two phylogenetic clades, where the predominant subtypes worldwide grouped together. In the temporal analysis, the tMRCA of BVDV-1 was 1336, and the diversification into different subtypes appears to have occurred around 363 years ago. The present results help to elucidate the origins of BVDV-1 subtypes and the dynamics of ruminant pestiviruses.

show abstract

supporting

confidence: 78%

mentioning

confidence: 99%

Insights into the origin and diversification of bovine viral diarrhea virus 1 subtypes

et al. 2021

View full text Add to dashboard Cite

show abstract

“…A third genetic species, BVDV type 3, described as atypical BVDV, has been reported [ 31 ] but officially remains unrecognized [ 32 ]. Based on the phylogenetic analysis of partial sequences from the 5’ UTR, Npro, glycoprotein E2, NS3, and NS5B-3’ UTR, BVDV-1 in cattle can be further differentiated into 21 genetic subtypes (BVDV-1a to BVDV-1u) [ 33 , 34 ] and BVDV-2 into four genetic subtypes (BVDV-2a – BVDV-2d) [ 35 , 36 ]. The genetic variability of BVDV-1 in goats was first reported in southwestern China.…”

Section: Discussionmentioning

confidence: 99%

First study on genetic variability of bovine viral diarrhea virus isolated from Sapera dairy goats with reproductive disorders in Yogyakarta, Indonesia

et al. 2022

View full text Add to dashboard Cite

Background and Aim: Bovine viral diarrhea (BVD) virus (BVDV) is an important viral pathogen of cattle that can infect diverse artiodactyl species. The clinical manifestations caused by BVDV in heterologous hosts, as they do in cattle, vary, although respiratory and reproductive failures are commonly reported. BVDV infections commonly result in reproductive failure in goats, with abortion being the primary clinical sign. In central Java, Indonesia, BVDV infection has been reported in two clinically healthy local goat species, and the testing indicated infection by BVDV Type 1. However, the genetic diversity of viruses has not been described in healthy or ill goats. The objectives of the present study were as follows: (1) To investigate the genetic variation of BVDV isolated from Sapera dairy goats with naturally occurring reproductive disorders in Yogyakarta, Indonesia, using the 5' untranslated region (5' UTR) and (2) to study the possible correlation between reproductive disorders and the presence of BVDV in the flock. Materials and Methods: Blood samples were collected in October 2021 from 39 goats that had been individually reported to have reproductive disorders. The serum samples were subjected to molecular detection and genetic characterization of BVDV based on the 5' UTR of the viral genome, followed by sequencing and phylogenetic analyses. Viral isolation was performed on BVDV-positive samples to analyze the viral biotypes. Results: BVDV infection was detected in five out of 39 female goats. The clinical status of the BVDV-infected goats was abortion (n=2), metritis (n=1), and repeated breeding (n=2). All antigen-positive samples were confirmed as BVDV type 1a (BVDV-1a) and noncytopathic (NCP)-BVDV biotype. Conclusion: The BVDV-1a and NCP biotypes are the main subtypes and biotypes present in Sapera dairy goats exhibiting reproductive failure. This result is consistent with previous results in dairy cattle in Yogyakarta. The reported results can facilitate the design of methods for the prevention and control of BVD circulating in Indonesia.

show abstract

“…The first type of virus is spread all over the world [1], but is found more often in the European countries. The largest number of subtypes (up to 21) was found in cattle in Italy [13] and China [14]. BVDV-2 in cattle was found in the USA [15], Canada [16], Brazil [17], Argentina [18], Uruguay [19], Germany [20], Slovakia [21], Italy [22], South Korea [23], Japan [24] and Mongolia [25].…”

Section: Introductionmentioning

confidence: 99%

Genetic Polymorphism of the Bovine Viral Diarrhea Viruses in Big Dairy Farms in Siberia

Koteneva¹,

Nefedchenko²,

Glotova³

et al. 2018

s-h. biol.

View full text Add to dashboard Cite

A b s t r a c tBovine viral diarrhea is a widespread disease in the Russian Federation and causes significant economic damage to dairy cattle, especially under intensive commercial farming. The seropositivity of livestock in various Russian regions reaches 65-100 %. The disease is caused by two different virus species, BVDV-1 and BVDV-2, of which the latter is considered more virulent. The persistently infected (PI) animals which are a constant endogenous source of the virus in the herd play a major role in maintaining the stationary trouble of the farms. Short-term sources of the pathogen are transitively infected (TI) animals in which disease proceeds in acute form. Genetic structure of viruses circulating in local livestock populations gives necessary information about the evolution, geography and pathways of the pathogen. However, studies on the genetic polymorphism of viruses in Russia are not enough. This paper is the first to report on a phylogenetic analysis of two types of viral diarrhea virus, isolated from animals of foreign and domestic origin with different clinical manifestations of the disease. These data show the prevalence of BVDV-1b in PI and TI animals, as well as BVDV-2b and BVDV-2c circulation among Siberian dairy complexes (note, BVDV-2b and BVDV-2c in animals of foreign and domestic origin are detected in Russia for the first time). Phylogenetic analysis of viruses circulating among PI and TI of highly productive dairy cattle was based on a comparison of conserved region of viral genome (5´-UTR) using reverse transcriptase PCR (RT-PCR) method. Studies were conducted in five regions of Western and Eastern Siberia: Tyumen, Novosibirsk, Irkutsk regions, the Krasnoyarsk Territory and Northern Kazakhstan on big dairy farms with a population of 800 or more milking cows with an average annual productivity of 7,000-10,000 liters, where at the time of the research vaccination was not carried out or inactivated vaccines were used. The imported livestock was kept mainly in the Tyumen region and the Republic of Kazakhstan. Biomaterial (blood, serum, nasal discharge, lymphoid organs, lungs, vaginal discharges) was collected from clinically healthy persistently infected animals, transitively infected animals with reproductive disorders and respiratory syndrome, as well as aborted fetuses. A total of 479 samples were examined. According to our findings, two BVDV species circulate among the PI and TI animals on the big dairy farms. The phylogenetic analysis reveals seven subtypes of BVDV-1, i.e. 1a (5 %), 1b (35 %), 1c (5 %), 1d (10 %), 1f (20 %), 1i (5 %), 1p (5 %) and two subtypes of BVDV-2, i.e. 2b (10 %) and 2c (5 %). Taking into account the fact that the strategy of livestock breeding is changing in Russia, the number of dairy mega farms" is increasing, which receive animals with different infectious status from many sources. Thence, the study of the genetic polymorphism of the virus is topical. Comparison of data on the origin of animals with the results of phylogenetic analyses can help in determina...

show abstract

Correction: Prevalence Study and Genetic Typing of Bovine Viral Diarrhea Virus (BVDV) in Four Bovine Species in China

Cited by 54 publications

References 2 publications

Insights into the origin and diversification of bovine viral diarrhea virus 1 subtypes

Insights into the origin and diversification of bovine viral diarrhea virus 1 subtypes

First study on genetic variability of bovine viral diarrhea virus isolated from Sapera dairy goats with reproductive disorders in Yogyakarta, Indonesia

Genetic Polymorphism of the Bovine Viral Diarrhea Viruses in Big Dairy Farms in Siberia

Contact Info

Product

Resources

About