“…The adoption of PEEK for PSIs production was influenced by its favorable properties, including radiolucent characteristics with no artifact in medical imaging, stiffness, lightweight, and conventional computer-aided design/computer-aided manufacturing (CAD/CAM) procedures, specifically milling [25,30]. Few studies have reported using custom-made, non-porous, milled PEEK implants in orbital reconstructions [19,31,32]. However, these non-porous characteristics displaying hydrophobicity and bio-inertness of PEEK can limit its bioactivity and cause clinical concern in orbital floor reconstructions [33,34].…”