2020
DOI: 10.1371/journal.pntd.0008724
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Correction: LAMP-2 absence interferes with plasma membrane repair and decreases T. cruzi host cell invasion

Abstract: Correction: LAMP-2 absence interferes with plasma membrane repair and decreases T. cruzi host cell invasion. PLoS Negl Trop Dis 14(9): e0008724.

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Cited by 2 publications
(2 citation statements)
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“…Noteworthy, LAMP-2 have shown to play a major role in cholesterol and caveolin traffic, membrane repair and T. cruzi invasion. Cells lacking LAMP-2 showed deficiency in cholesterol delivered to the plasma membrane and an altered caveolin-1 distribution, both phenomena being refractory to TCTs invasion ( do Couto et al, 2020 ). Similarly, MTs internalization was significantly reduced in LAMP-2-depleted HeLa cells ( Cortez et al, 2016 ).…”
Section: Hijacking Host’s Signaling Machinerymentioning
confidence: 99%
“…Noteworthy, LAMP-2 have shown to play a major role in cholesterol and caveolin traffic, membrane repair and T. cruzi invasion. Cells lacking LAMP-2 showed deficiency in cholesterol delivered to the plasma membrane and an altered caveolin-1 distribution, both phenomena being refractory to TCTs invasion ( do Couto et al, 2020 ). Similarly, MTs internalization was significantly reduced in LAMP-2-depleted HeLa cells ( Cortez et al, 2016 ).…”
Section: Hijacking Host’s Signaling Machinerymentioning
confidence: 99%
“…Exocytosis of lysosomes enriched in cholesterol impairs the caveolin-1 distribution at the cell surface and prevents endocytosis. Thus, LAMP2 is crucial for the ability to perform endocytosis of lysosome-derived membrane parts [ 189 ]. Alternatively, the plasma membrane patch is removed by shedding the membrane through the generation of ectosomes.…”
Section: Secretion From the Lysosomal Pathwaymentioning
confidence: 99%