Correction for Takano et al., “Vital Role of the Calpain-Calpastatin System for Placental-Integrity-Dependent Embryonic Survival”

Overproduction and identification of butyrolactones SCB1–8 in the antibiotic production superhost Streptomyces M1152

“…[8][9][10][11] SCBs act as antibiotic production inducers and directly control the expression of a cluster of genes, named cpk, responsible for the biosynthesis of the coelimycin polyketide antibiotic in S. coelicolor. 12,13 The molecular mode of action of SCBs involves direct binding to the transcriptional repressor ScbR. In the absence of SCBs, ScbR binds to specific operator sequences in particular upstream of the transcriptional activator cpkO and prevents coelimycin production.…”