Correction for Rossetto et al., Regulation of Viral and Cellular Gene Expression by Kaposi's Sarcoma-Associated Herpesvirus Polyadenylated Nuclear RNA

Rossetto, Cyprian C.; Tarrant-Elorza, Margaret; Verma, Subhash C.; Purushothaman, Pravinkumar; Pari, Gregory S.

doi:10.1128/jvi.00171-16

Cited by 4 publications

(4 citation statements)

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“…Whether and how disease-associated SNPs alter human NeST expression and/or function has not been elucidated and should be addressed in future studies. Nucleus Serves as a structural scaffold for the formation of nuclear paraspeckles; enhances HIV production; facilitates the expression of antiviral genes including cytokines such as IL-8 by cooperative action of NEAT1 and SFPQ Guru et al, 1997;Saha et al, 2006;Bond and Fox, 2009;Clemson et al, 2009;Sasaki et al, 2009;Sunwoo et al, 2009;Zhang et al, 2013;Imamura et al, 2014 EGOT Regulates gene expression through epigenetic mechanisms; interacts with several virus-and host cell-encoded factors; and promotes LANA-episome disassociation through an interaction with LANA Sun et al, 1996;Ballestas et al, 1999;Borah et al, 2011;Rossetto and Pari, 2011Rossetto et al, 2013Rossetto et al, , 2016 LncRNA NRON (non-coding repressor of NFAT) was initially identified as an inhibitor of transcription factor NFAT (Willingham et al, 2005). NRON interacts with KPNB1, CSE1L, and IQGAP1, which bind phosphorylated NFAT in cytoplasm and represses NFAT nuclear trafficking.…”

Section: Cellular Lncrnas In Virus-infected Cellsmentioning

confidence: 99%

“…PAN binds host poly (A)binding protein C1 (PABPC1) after PABPC1 is translocated to the nucleus during the lytic phase of infection and is required for the late KSHV gene expression, such as vIL-6 and k8.1 (Borah et al, 2011). PAN also interacts with the ORF50 promoter and can either repress gene expression by interacting with protein components of polycomb repression complex 2 (PRC2) to mediate the trimethylation of H3K27 or activate gene expression by interacting with UTX, JMJD3 and the histone methyltransferase MLL2 to mediate the removal of the H3K27me3 mark and simultaneously mark it for activation (Rossetto and Pari, 2012;Rossetto et al, 2013Rossetto et al, , 2016.…”

Section: Virus-encoded Lncrnamentioning

confidence: 99%

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Roles of LncRNAs in Viral Infections

Liu

Chen

2017

Front. Cell. Infect. Microbiol.

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Many proteins and signaling pathways participate in anti-viral host responses. Long non-coding RNAs (lncRNAs), a subset of non-coding RNAs greater than 200 nucleotides in length, have been recently described as critical regulators in viral infections. Accumulating research indicates that lncRNAs are important in the development and progression of infectious diseases. LncRNAs are not only involved in anti-viral responses, but in many different virus-host interactions, some of which may be beneficial to the virus. Here we review the current knowledge regarding host and viral lncRNAs and their roles in viral infections. In addition, the potential of using lncRNAs as diagnostic biomarkers is discussed.

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Section: Cellular Lncrnas In Virus-infected Cellsmentioning

confidence: 99%

Section: Virus-encoded Lncrnamentioning

confidence: 99%

Roles of LncRNAs in Viral Infections

Liu

Chen

2017

Front. Cell. Infect. Microbiol.

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“…PAN RNA plays an important function in controlling viral gene expression and propagation and is involved in subversion of the host immune response ( 71 , 72 ). PAN RNA typically influences cellular and viral gene expression via binding with host proteins, including histone methyltransferase MLL2, histones H1 and H2A, the demethylase UTX, poly (A)-binding protein C1, IFN regulatory factor 4, and polycomb repression complex 2 proteins SUZ12, EZH2, and JMJD3 ( 73 , 74 ). Its interactions with histone-modifying complexes eliminate the suppressive H3K23me3 mark on the KSHV genome, thus activating lytic replication (Figure 1 C).…”

Section: Polyadenylated Nuclearmentioning

confidence: 99%

Long Non-Coding RNAs: Novel Players in Regulation of Immune Response Upon Herpesvirus Infection

Waqas

Liu

2018

Front. Immunol.

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Herpesviruses have developed a variety of sophisticated immune evasion strategies to establish lifelong latent infection, including the use of long non-coding RNAs (lncRNAs). In this review, we summarize the lncRNA action modes, i.e., RNA–protein, RNA–RNA, and RNA–DNA interactions, involved in regulating important aspects of immunity by controlling gene expression at various stages. Upon herpesvirus infection, host lncRNAs, such as nuclear paraspeckle assembly transcript 1, negative regulator of antiviral, and B-cell integration cluster have been functionally characterized as negative or positive antiviral regulators in the immune response. Herpesviruses have also evolved multiple strategies to modulate the host immune response using lncRNAs, such as latency-associated transcript, β 2.7 RNA, 5 kb and 7.2 kb lncRNAs, Epstein–Barr virus-encoded non-coding RNA, BamH I-A rightward transcripts, polyadenylated nuclear, and herpesvirus saimiri U-rich RNAs. We discuss the various mechanisms of immune-related lncRNAs, and their diversified and important functions in the modulation of innate and adaptive immunity upon herpesvirus infection as well as in host–pathogen interactions, which will facilitate our understanding of rational design of novel strategies to combat herpesvirus infection.

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“…A tinea negra representa uma infecção fúngica crônica, superficial, rara e assintomática da camada córnea causada pelo fungo Phaeoannellomyces werneckii, também denominado Hortaea werneckii. Trata-se de um fungo saprófito encontrado em solo, plantas, ambientes úmidos e regiões de alta concentração salina, como a areia da praia 1,2 . Esta dermatose é mais prevalente em regiões tropicais e subtropicais 1,3 .…”

Section: Introductionunclassified

Tinea Negra Simulando Melanoma

Vasconcelos¹,

Bello²,

Pugliesi³

et al. 2018

Rev Pat Tocantins

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RESUMO A tinea negra caracteriza-se como uma infecção fúngica rara à camada córnea, causada pelo fungo Phaeoannellomyces werneckii. É notória a semelhança entre casos dessa dermatofitose e do melanoma, e sua diferenciação é preconizada para evitar procedimentos invasivos. Tratando-se de uma doença rara e ainda menos incidente no estado, descreve-se uma paciente de 33 anos do sexo feminino, apresentando mácula plantar entre o terceiro e quarto pododáctilos direto, com hifas marrons claras entrecruzadas à dermatoscopia. Diagnóstico confirmado com exame micológico direto. O diagnóstico pode ser potencializado pelo uso do dermatoscópio, cujo acesso tem evoluído, mas é confirmado com exame micológico direto. Palavras chave: tinea negra; melanoma; dermatoscopia; dermatofitose.

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Correction for Rossetto et al., Regulation of Viral and Cellular Gene Expression by Kaposi's Sarcoma-Associated Herpesvirus Polyadenylated Nuclear RNA

Cited by 4 publications

References 0 publications

Roles of LncRNAs in Viral Infections

Roles of LncRNAs in Viral Infections

Long Non-Coding RNAs: Novel Players in Regulation of Immune Response Upon Herpesvirus Infection

Tinea Negra Simulando Melanoma

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