Correction: Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment

Lores, Saínza; Gámez-Chiachio, Manuel; Cascallar, María; Ramos-Nebot, Carmen; Hurtado, Pablo; Alijas, Sandra; López, Rafael; Piñeiro, Roberto; Moreno‐Bueno, Gema; Fuente, María de la

doi:10.1039/d3bm90029k

Biomater. Sci.

2023

DOI: 10.1039/d3bm90029k

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Correction: Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment

Saínza Lores

Manuel Gámez-Chiachio

María Cascallar

et al.

Abstract: Correction for ‘Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment’ by Saínza Lores et al., Biomater. Sci., 2023, https://doi.org/10.1039/d2bm01456d.

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The significant role of amino acid metabolic reprogramming in cancer

Liu,

Ren,

Ren

et al. 2024

Cell Commun Signal

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Amino acid metabolism plays a pivotal role in tumor microenvironment, influencing various aspects of cancer progression. The metabolic reprogramming of amino acids in tumor cells is intricately linked to protein synthesis, nucleotide synthesis, modulation of signaling pathways, regulation of tumor cell metabolism, maintenance of oxidative stress homeostasis, and epigenetic modifications. Furthermore, the dysregulation of amino acid metabolism also impacts tumor microenvironment and tumor immunity. Amino acids can act as signaling molecules that modulate immune cell function and immune tolerance within the tumor microenvironment, reshaping the anti-tumor immune response and promoting immune evasion by cancer cells. Moreover, amino acid metabolism can influence the behavior of stromal cells, such as cancer-associated fibroblasts, regulate ECM remodeling and promote angiogenesis, thereby facilitating tumor growth and metastasis. Understanding the intricate interplay between amino acid metabolism and the tumor microenvironment is of crucial significance. Expanding our knowledge of the multifaceted roles of amino acid metabolism in tumor microenvironment holds significant promise for the development of more effective cancer therapies aimed at disrupting the metabolic dependencies of cancer cells and modulating the tumor microenvironment to enhance anti-tumor immune responses and inhibit tumor progression.

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The significant role of amino acid metabolic reprogramming in cancer

Liu,

Ren,

Ren

et al. 2024

Cell Commun Signal

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Correction: Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment

Abstract: Correction for ‘Effectiveness of a novel gene nanotherapy based on putrescine for cancer treatment’ by Saínza Lores et al., Biomater. Sci., 2023, https://doi.org/10.1039/d2bm01456d.

Cited by 1 publication

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The significant role of amino acid metabolic reprogramming in cancer

The significant role of amino acid metabolic reprogramming in cancer

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