Correction: De Conti et al. Histological Lesions and Replication Sites of PCV3 in Naturally Infected Pigs. Animals 2021, 11, 1520

Conti, Elisa Rigo De; Resende, Talita Pilar; Marshall-Lund, Lacey; Rovira, Albert; Vannucci, Fábio A.

doi:10.3390/ani11113277

Cited by 3 publications

(2 citation statements)

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“…It seems likely that the K-shell emission that occurred in the TDPN mode during the development of the instabilities was provided by hot spots. As noted by Lavine et al [37] and Conti et al [39], such hot spots can be formed stochastically in an unstable pinch.…”

Section: Shotmentioning

confidence: 83%

Effect of tailored density profiles on the stability of imploding Z-pinches at microsecond rise time megaampere currents

Cherdizov¹,

Baksht²,

Kokshenev³

et al. 2021

Plasma Phys. Control. Fusion

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To study the effect of the radial density profile of the material of a metal-plasma Z-pinch load on the development of magneto-Rayleigh-Taylor (MRT) instabilities, experiments have been performed at the Institute of High Current Electronics with the GIT-12 generator produced microsecond rise time megaampere currents. The load was an aluminum plasma jet with an outer plasma shell. This configuration provides the formation of a uniform current sheath in a Z-pinch load upon application of a high voltage pulse. It was successfully used in experiments with hybrid deuterium gas-puffs [Klir et al. 2020 New J. Phys. 22 103036]. The initial density profiles of the Z-pinch loads were estimated from the pinch current and voltage waveforms using the zero-dimensional "snowplow" model, and they were verified by simulating the expansion of the plasma jet formed by a vacuum arc using a two-dimensional quasi-neutral hybrid model [Shmelev et al. 2020 Phys. Plasmas 27 092708]. Two Z-pinch load configurations were used in the experiments. The first configuration provided tailored load density profiles, which could be described as ρ(r) ≈ 1/r^s for s > 2. In this case, MRT instabilities were suppressed and thus a K-shell radiation yield of 11 kJ/cm and a peak power of 0.67 TW/cm could be attained at a current of about 3 MA. For the second configuration, the radial density profiles were intentionally changed using a reflector. This led to the appearance of a notch in the density profiles at radii of 1–3 cm from the pinch axis and to magnetohydrodynamic instabilities at the final implosion stage. As a result, the K-shell radiation yield more than halved and the power decreased to 0.15 TW/cm at a current of about 3.5 MA.

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Section: Shotmentioning

confidence: 83%

Effect of tailored density profiles on the stability of imploding Z-pinches at microsecond rise time megaampere currents

Cherdizov¹,

Baksht²,

Kokshenev³

et al. 2021

Plasma Phys. Control. Fusion

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show abstract

“…2,23 Our results also suggest a potential role of PCV3 in interstitial pneumonia. Interstitial pneumonia has been described in PCV3-positive pigs in other case reports 6,23,29 and in one experimental infection trial. 13 It is important to note that the PCV3 PCR test in our study was performed for each pig on a homogenate of multiple tissues, not on individual tissues.…”

Section: Discussionmentioning

confidence: 75%

Frequency of porcine circovirus 3 detection and histologic lesions in clinical samples from swine in the United States

Yang

Marthaler²,

Rovira

2022

J VET Diagn Invest

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Porcine circovirus 3 (PCV3) is widespread in pigs worldwide. Diverse clinical signs and lesions have been associated with PCV3, but the role of PCV3 as a cause of disease in swine remains unclear. We investigated the association of PCV3 with clinical signs and histologic lesions in 730 diagnostic swine cases between February 2016 and January 2018. The cases contained 2,177 samples submitted from 474 sites located in 21 states in the United States. PCR assay results were positive for PCV3 for 577 of 2,177 (27%) samples, 255 of 730 (35%) cases, 181 of 474 (38%) sites, and 17 of 21 (81%) states. We detected PCV3 in 19 of 28 specimen types and in pigs of all ages and clinical presentations, including healthy pigs, with the highest detection rate in adult pigs. PCV3 detection was not associated with respiratory, gastrointestinal, or CNS signs, weight loss, or sudden death. Of 58 types of histologic lesions evaluated, PCV3 detection was associated with myocarditis, cardiac vasculitis, and interstitial pneumonia in growing pigs. A high PCV3 detection rate was observed in aborted fetuses.

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Exploratory Study of the Frequency of Detection and Tissue Distribution of Porcine Circovirus 3 (PCV-3) in Pig Fetuses at Different Gestational Ages

et al. 2022

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Porcine circovirus 3 (PCV-3) has been associated with several pig diseases. Despite the pathogenicity of this virus has not been completely clarified, reproductive disorders are consistently associated with its infection. The aim of the present work was to analyze the presence of PCV-3 DNA in tissues from pig fetuses from different gestational timepoints. The fetuses were obtained either from farms with no reproductive problems (NRP, n = 249; all of them from the last third of gestation) or from a slaughterhouse (S, n = 51; 49 of the second-third of gestation and 2 from the third one). Tissues collected included brain, heart, lung, kidney, and/or spleen. Overall, the frequency of detection of PCV-3 was significantly higher in fetuses from the last third of the gestation (69/251, 27.5%) when compared to those from the second-third (5/49, 10.2%), although the viral loads were not significantly different. Moreover, the frequency of detection in NRP fetuses (69/249, 27.7%) was significantly higher than in S ones (5/51, 9.8%). Furthermore, PCV-3 DNA was detected in all tissue types analyzed. In conclusion, the present study demonstrates a higher frequency of PCV-3 DNA detection in fetuses from late periods of the gestation and highlights wide organ distributions of the virus in pig fetuses.

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Correction: De Conti et al. Histological Lesions and Replication Sites of PCV3 in Naturally Infected Pigs. Animals 2021, 11, 1520

Abstract: The authors wish to make the following correction to this paper [...]

Cited by 3 publications

References 1 publication

Effect of tailored density profiles on the stability of imploding Z-pinches at microsecond rise time megaampere currents

Effect of tailored density profiles on the stability of imploding Z-pinches at microsecond rise time megaampere currents

Frequency of porcine circovirus 3 detection and histologic lesions in clinical samples from swine in the United States

Exploratory Study of the Frequency of Detection and Tissue Distribution of Porcine Circovirus 3 (PCV-3) in Pig Fetuses at Different Gestational Ages

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