Correction: Corrigendum: Relationship between nanotopographical alignment and stem cell fate with live imaging and shape analysis

Abstract

Scientific Reports 6: Article number: 37909; published online: 02 December 2016; updated: 07 March 2017. The original version of this Article contained an error in the spelling of the author Jorge Luis Galeano Niño, which was incorrectly given as Jorge Luis Galenano-Niño. Additionally, there were typographical errors in Affiliation 9 which was incorrectly listed as ‘Sydney Medical School, The University of Sydney, NSW, 2006, Australia.

Current Approaches to Bone Tissue Engineering: The Interface between Biology and Engineering

“…In another study, substrates with aligned and random nanotopographies were fabricated by coating the surface of glass coverslips with carbon nanotubes (CNTs) (Figure 2B). [47] ASCs cultured on the aligned and random nanotopographies showed distinct differences in cell behavior. While the random topography caused cells to become more circular, the aligned topography caused cells to have an elongated shape that resulted in high expression of early stage markers of myogenic differentiation, suggesting commitment towards satellite cell muscle progenitors.…”

“…Specifically, the osteogenesis or neurogenesis of hMSCs was enhanced by nanogrooves with a 1:3 spacing ratio rather than 1:1 or 1:5. In another study, substrates with aligned and random nanotopographies were fabricated by coating the surface of glass coverslips with carbon nanotubes (Figure B) . ASCs cultured on the aligned and random nanotopographies showed distinct differences in cell behavior.…”

“…B) Random and aligned nanotopographies created using carbon nanotubes (left panel) influenced the shape of attached cells (right panel), resulting in different differentiation outcomes in human adipose tissue-derived mesenchymal stem cells; scale bar: 100 µm. Adapted with permission [47]. Copyright 2016, Nature Publishing Group.…”

Magnetically Assisted Electrodeposition of Aligned Collagen Coatings

“…When BMSCs are seed on the aligned collagen coatings, the collagen nanofibers guide the cells to grow along the nanofiber direction to form elongated morphology (Figure ), with the afterward promoted cell adhesion, proliferation and differentiation, as well as mRNA expression of osteogenic markers (Figure ). As is well-known, cell spreading is partially guided by focal adhesions that form and distribute between cells and materials, mediated by integrins on the cell membrane . Previous studies have demonstrated that nanofiber alignment-induced formation of focal adhesion might mainly appear on the front edge of the elongated cells and parallel to the aligned nanofibers, which in turn resulted in the elongation of F-actin along the fiber direction, followed by the changes of genes transcriptions. , We therefore speculated the up-regulated osteogenic genes expression may be attributed to the alignment of the integrin-mediated actin elongation and arrangement.…”