2017
DOI: 10.1038/srep46011
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Correction: Corrigendum: New insights into the intracellular distribution pattern of cationic amphiphilic drugs

Abstract: The Acknowledgements section in this Article is incomplete. "NeuroNova gGmbH, Munich provided financial support between 2011 and 2016 aiming at The investigation of novel molecular mechanisms of antidepressants at cellular level". should read: "NeuroNova gGmbH, Munich provided financial support between 2011 and 2016 aiming at The investigation of novel molecular mechanisms of antidepressants at cellular level. C.B. and L.M. thank the excellence clusters Nanosystems Initiative Munich (NIM) and the Center for In… Show more

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“…Many of the observations from Tummino et al were perhaps not surprising as much has already been written about CADs, such as their intracellular accumulation in different subcellular compartments (e.g., mitochondria and lysosomes). , Basic amines like chloroquine may also lead to accumulation in these compartments and change the pH, which ultimately inhibits entry for some viruses. The alkalinization of acidic components, like the lysosome, in such host cells has previously been proposed as a strategy to decrease SARS-CoV-2 viral infection .…”
mentioning
confidence: 99%
“…Many of the observations from Tummino et al were perhaps not surprising as much has already been written about CADs, such as their intracellular accumulation in different subcellular compartments (e.g., mitochondria and lysosomes). , Basic amines like chloroquine may also lead to accumulation in these compartments and change the pH, which ultimately inhibits entry for some viruses. The alkalinization of acidic components, like the lysosome, in such host cells has previously been proposed as a strategy to decrease SARS-CoV-2 viral infection .…”
mentioning
confidence: 99%