Corrected transposition of the great vessels without associated defects

Rotem, C. E.; Hultgren, Herbert N.

doi:10.1016/0002-8703(65)90178-x

Cited by 28 publications

(8 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In fact, of 24 "9uncomplicated" cases collected by Rotem and Hultgren, only three were free of these complications. 4 The present patient seems to have been unusually fortunate in many respects. The mitral insufficiency was probably late in onset and not of a severe degree.…”

mentioning

confidence: 63%

“…This complication appears to be of major significance in the death of three patients without other complications at the age of 35, 36, and 45 years, respectively. [1][2][3][4][5][6][7][8][9][10][11][12][13] The relationship of the mild aortic insufficiency to the patient's other congenital lesion is difficult to determine. There was no evidence of syphilis of the aorta, and no evidence of aortic, aortic ring, or aortic valvular diseases at postmortem examination.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Corrected Transposition of the Great Vessels in a 73-Year-Old Man

et al. 1969

View full text Add to dashboard Cite

SUMMARYThe case of a 73-year-old white man with corrected transposition of the great vessels and associated mitral and mild aortic regurgitation is reported. The patient's survival was the longest of any patient with this defect reported to date. Although the condition is theoretically compatible with a normal life span, few patients with this lesion survive past 40 years of age because of associated congenital defects or the subsequent development of A-V valvular insufficiency or heart block, or both. Additional Indexing Words:Mitral insufficiency

show abstract

mentioning

confidence: 63%

mentioning

confidence: 99%

Corrected Transposition of the Great Vessels in a 73-Year-Old Man

et al. 1969

View full text Add to dashboard Cite

show abstract

“…Clinical RV failure, however, may be expected to be a relatively late event, since the rare patients with congenitally corrected transposition of the great arteries, and without other abnormalities, may live to more than 35 years before RV failure develops (25,32). The risk of RV failure is the main reason for preferring anatomic correction to the simpler Senning or Mustard procedures, although arrhythmias may be less frequent after the switch operation (3).…”

Section: Discussionmentioning

confidence: 99%

Long-term follow-up of right ventricular function after mustard operation for transposition of the great arteries

Buch¹,

Wennevold²,

Jacobsen³

et al. 1988

Scandinavian Journal of Thoracic and Cardiovascular Surgery

View full text Add to dashboard Cite

As development of right ventricular (RV) failure is a potential risk after Mustard operation for transposition of the great arteries, 17 patients were reexamined 5-13 years postoperatively. Comparisons were made with healthy controls. There were no clinical signs of heart failure. Echocardiographically determined RV end-diastolic diameter was increased to 2.5 +/- 0.8 cm (controls: 1.5 +/- 0.4 cm, p less than 0.001). Comparison of RV systolic time intervals (STI) in patients with normal left ventricular (LV) STI revealed decreased RV function, with RPEPI 165 +/- 19 msec (controls 126 +/- 12, p less than 0.001) and RPEP/RVET 0.484 +/- 0.096 (controls 0.284 +/- 0.045, p less than 0.001). Nuclear angiography demonstrated decreased RV ejection fraction (EF), viz. 42.8 +/- 6.6% (normal RV 53 +/- 6%, LV 68 +/- 9%, p less than 0.001). Only two patients showed normal (5%) rise in RV-EF during exercise. There was no evidence of deterioration with passage of time. The results do not justify use of anatomic repair at our center, since the perioperative mortality might then be higher than in the Mustard or Senning procedures.

show abstract

“…Congenital corrected transposition of the great arteries (CTGA) is usually accompanied by additional cardiac malformations but may occur without associated defects (Rotem and Hultgren, 1965). Atrioventricular conduction disturbances are found in almost half of the patients (Schiebler et al, 1961;Friedberg and Nadas, 1970), the commonest being a prolonged PR interval.…”

mentioning

confidence: 99%

Complete heart block in an adult with corrected transposition of the great arteries treated with permanent pacemaker.

Amikam¹,

Lemer²,

Kishon³

et al. 1979

Thorax

View full text Add to dashboard Cite

A 53-year-old patient with corrected transposition of the great arteries developed complete heart block with fainting episodes. After temporary pacing through the endocardium of the venous (anatomically left) ventricle, a permanent epicardial pacemaker was implanted. This case shows the progressive nature of the atrioventricular conduction disturbances, which are very common in association with this congenital cardiac anomaly.Congenital corrected transposition of the great arteries (CTGA) is usually accompanied by additional cardiac malformations but may occur without associated defects (Rotem and Hultgren, 1965). Atrioventricular conduction disturbances are found in almost half of the patients (Schiebler et al, 1961;Friedberg and Nadas, 1970), the commonest being a prolonged PR interval. When complete heart block is present, the QRS complex is narrow, the ventricular rate is usually greater than 50/min, and rarely dominates the clinical picture, which is determined by the additional anatomical abnormalities (Shem-Tov et al, 1971). The few reported cases of CTGA in whom complete heart block necessitated pacemaker implantation were in children who developed this conduction disturbance in infancy, early childhood, or adolescence (Friedberg and Nadas, 1970) and only in one instance in an adult patient (Berman and Adicoff, 1969).We describe a middle-aged patient in whom CTGA was first diagnosed at the age of 49 and who at the age of 53 developed complete atrioventricular block that required pacemaker implantation. This is the second reported adult case in whom a permanent pacemaker was implanted to treat complete heart block in the presence of CTGA. Case reportA 53-year-old clerk was transferred to the department of cardiology at the Rambam Medical Centre with a three-day history of pronounced weakness, dyspnoea on minimal effort, and two episodes of Stokes-Adams attacks. During these episodes a slow heart rate (30/min) was recorded, and the electrocardiogram showed complete atrioventricular block.In 1970, at the age of 46, he had begun to suffer from recurrent episodes of left heart failure and was treated with digitalis and diuretics. As he did not fully respond to this treatment he was admitted in 1973 to the heart institute of the Haim Sheba Medical Centre, where right and left heart catheterisations were performed, and the diagnosis of CTGA was established. In addition, a moderate degree of aortic regurgitation and slight left atrioventricular valve regurgitation were shown. The electrocardiogram in 1973 showed sinus rhythm with a PR interval of 0-36 seconds. The patient was discharged home, remained well, and continued to work.At the present admission he was dyspnoeic and orthopnoeic with an irregular pulse of 54/min and a blood-pressure of 120/70 mmHg. There was no jugular venous congestion. Fine crepitations were heard at both lung bases. The apex beat was not palpable, but he had a left parasternal heave. A single and accentuated second heart sound, a 3/6 ejection systolic murmur, and a 2/6 early d...

show abstract

Corrected transposition of the great vessels without associated defects

Cited by 28 publications

References 19 publications

Corrected Transposition of the Great Vessels in a 73-Year-Old Man

Corrected Transposition of the Great Vessels in a 73-Year-Old Man

Long-term follow-up of right ventricular function after mustard operation for transposition of the great arteries

Complete heart block in an adult with corrected transposition of the great arteries treated with permanent pacemaker.

Contact Info

Product

Resources

About