Coronavirus Disease 2019–Related Health Disparities in Ophthalmology with a Retrospective Analysis at a Large Academic Public Hospital

Chung, Yooree G; Person, Christie M.; O’Banion, Jacquelyn; Primo, Susan A.

doi:10.1016/j.yaoo.2022.04.005

Cited by 3 publications

(3 citation statements)

References 53 publications

(59 reference statements)

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“…Moreover, cases of optic neuritis, retinal vaso-occlusion and intracranial hypertension have been observed in positive COVID-19 patients. Oscillopsia, ataxia or myoclonus were also described in several case reports as being associated with SARS-CoV-2 infection [39,40].…”

Section:  Implications At Ocular Level Of Mirnas Modifications Induc...mentioning

confidence: 78%

“…The molecular mechanism of SARS-CoV-2 presence in the eye, relies on the interaction between the host ACE2 cellular receptor and the virus S protein. This receptor is located in retina, aqueous humor, retinal pigment epithelium (RPE), choroid, and conjunctival epithelium [38,39]. The clinical manifestations of SARS-CoV-2 infection at the ocular level involve a wide variety of symptoms frequently associated with keratoconjunctivitis.…”

Section:  Implications At Ocular Level Of Mirnas Modifications Induc...mentioning

confidence: 99%

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Implications at the ocular level of miRNAs modifications induced by SARS-CoV-2 infection

Milcu¹,

Anghel²,

Mușat³

et al. 2022

Rom J Morphol Embryol

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The coronavirus disease 2019 (COVID-19) pandemic determined the use of different research methods and investigations in the management of this novel infectious disease. The impact and development of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) at cellular level is still a challenge and many directions of investigation have been opened, a complex topic that has been explored is the bidirectional interaction between host micro-ribonucleic acids (miRNAs) and viral miRNA. The main point of this study is to analyze the transcriptional modifications induced by the viral infection at ocular level, mediated by miRNAs. It is known that the ocular transmission is a route of infection, and it can cause multiple neuro-ophthalmological manifestations, such as optic nerve dysfunction, eye movement abnormalities, oscillopsia and intracranial hypertension. We have managed to identify more than six miRNAs specifically involved in eye disorders that are strongly dysregulated by the SARS-CoV-2. These miRNAs regulate different pathways, such as the nuclear factor-kappa B (NF-κB) pathway, the expression of complement factor H (CFH) gene, the expression of transforming growth factor-beta (TGF-β), fibroblast growth factor (FGF) and platelet-derived growth factor (PDGF) genes. In the context of SARS-CoV-2 infection, many more molecular changes at ocular level need to be elucidated to better understanding the COVID-19.

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Section:  Implications At Ocular Level Of Mirnas Modifications Induc...mentioning

confidence: 78%

Section:  Implications At Ocular Level Of Mirnas Modifications Induc...mentioning

confidence: 99%

Implications at the ocular level of miRNAs modifications induced by SARS-CoV-2 infection

Milcu¹,

Anghel²,

Mușat³

et al. 2022

Rom J Morphol Embryol

View full text Add to dashboard Cite

show abstract

“…Disparities related to patient demographics during the COVID-19 pandemic have gradually gained prevalence in the ophthalmic literature (Chung et al 2022). A study of ophthalmic patients at an academic ophthalmic center during the COVID-19 pandemic revealed that patients who were older and who identified as male, Black, or non-English speaking were associated with decreased receipt of teleophthalmology care (Aziz et al 2021, Chen et al 2022.…”

Section: Patient Demographicsmentioning

confidence: 99%

Disparities in Eye Care Access and Utilization: A Narrative Review

Andoh

Ezekwesili

Nwanyanwu

et al. 2023

Annu. Rev. Vis. Sci.

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This narrative review summarizes the literature on factors related to eye care access and utilization in the United States. Using the Healthy People 2030 framework, this review investigates social determinants of health associated with general and follow-up engagement, screenings, diagnostic visits, treatment, technology, and teleophthalmology. We provide hypotheses for these documented eye care disparities, featuring qualitative, patient-centered research. Lastly, we provide recommendations in the hopes of appropriately eliminating these disparities and reimagining eye care. Expected final online publication date for the Annual Review of Vision Science, Volume 9 is September 2023. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.

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Evolution of Disparities in Outpatient Ophthalmic Care at a Tertiary Care Center in California at the Beginning of and One Year into the COVID-19 Public Health Emergency

Shen

Gutierrez

Villegas

et al. 2023

Ophthalmic Epidemiology

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Coronavirus Disease 2019–Related Health Disparities in Ophthalmology with a Retrospective Analysis at a Large Academic Public Hospital

Cited by 3 publications

References 53 publications

Implications at the ocular level of miRNAs modifications induced by SARS-CoV-2 infection

Implications at the ocular level of miRNAs modifications induced by SARS-CoV-2 infection

Disparities in Eye Care Access and Utilization: A Narrative Review

Evolution of Disparities in Outpatient Ophthalmic Care at a Tertiary Care Center in California at the Beginning of and One Year into the COVID-19 Public Health Emergency

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