2021
DOI: 10.1016/j.intimp.2021.108049
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Coronavirus disease-2019: A review on the disease exacerbation via cytokine storm and concurrent management

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Cited by 16 publications
(23 citation statements)
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References 118 publications
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“…Dear Editor, In 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China. 1 It is one of the most serious health threats currently facing the world. More than 700 million people have contracted this virus to this point, with an estimated 6.5 million succumbing to it so far; the toll is still rising.…”
mentioning
confidence: 99%
“…Dear Editor, In 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China. 1 It is one of the most serious health threats currently facing the world. More than 700 million people have contracted this virus to this point, with an estimated 6.5 million succumbing to it so far; the toll is still rising.…”
mentioning
confidence: 99%
“…Because of how quickly it spread and the havoc it caused; it was declared an international public health emergency not long after it first appeared. On March 2020, the World Health Organization (WHO) declared a global pandemic in response to the new coronavirus (COVID‐19) outbreak 1 . The intensity, mortality, and hospitalization rates of the pandemic have varied across areas as it has progressed.…”
Section: Disease Salient Clinical Features Number Of Cases (Reported ...mentioning
confidence: 99%
“…Vaccination is the most reliable preventative measure; hence it must be made accessible to individuals from all socioeconomic backgrounds. However, public health in low‐ and middle‐income nations is difficult to ensure because of the difficulty of obtaining vaccines at the right time 1 . If vaccinations are not readily available, the health care sector will need to identify alternate practices and treatments to mitigate dangers, as well as develop new rules about these methods of treatment.…”
Section: Disease Salient Clinical Features Number Of Cases (Reported ...mentioning
confidence: 99%
“…The hyperactivation of innate immunity signalling pathways following SARS-CoV-2 infection can lead to massive systemic inflammation, also known as a cytokine storm, which is the main cause of multi-organ damage and death [ 8 ].…”
Section: Introductionmentioning
confidence: 99%