Coronary Vasospasm in an Adolescent Resulting from Marijuana Use

Abstract

This report is the first to describe coronary vasospasm, diagnosed by cardiac magnetic resonance imaging in an adolescent, resulting from marijuana abuse. A previously healthy 17-year-old male patient with severe chest pain, electrocardiographic changes, and urine test positive for cannabis, was diagnosed of having transient myocardial ischemia. The patient was discharged home and at this writing remains asymptomatic with a follow-up echocardiogram after 1 month showing normal left ventricular systolic function. Marijuana should be considered in the etiology of transient coronary vasospasm leading to myocardial ischemia in otherwise healthy adolescents. Cardiac magnetic resonance imaging is a safe and effective method for diagnosing coronary vasospasm.

Myocardial infarction following cannabis induced coronary vasospasm

“…In-vitro studies have shown that cannabis may have procoagulant effects, through increased expression of glycoprotein 11b-111a and P-selectin on platelets 6. Vasospasm may also occur, similar to cocaine use 7. Several case reports have documented MI triggered by marijuana use.…”

Acute Myocardial Infarction in a Young Man; Fatal Blow of the Marijuana: A Case Report

“…Marijuana has various effects, such as vasoconstriction or vasodilation on different vascular beds and, may also cause coronary vasospasm or slow coronary flow (SCF) by its sympathetic or minimal pressor effects, especially in patients with atherosclerotic lesions present 2)4)9)12)15-17). Karabulut and Cakmak12) reported a case of inferior MI in a patient who had consumed marijuana regularly over a long period and whose coronary angiography demonstrated SCF.…”

Anterior Myocardial İnfarction and Developing Ventricular Aneurysm After Cannabis Use

“…Vakamızda akut MI'ın koroner trombüs ihtimalinin yanında koroner spazm nedeni ile de oluşmuş olabileceği kanısındayız. Daha önce mariuana kullanımına bağlı koroner vazospazm geliştiği magnetik rezonans ile gösterilmiştir [7]. Koroner vazospazma bağlı ventriküler anevrizma gelişmesi sık rastlanılan bir durum değildir, bu yönüyle de vakamız ayrı bir özellik arz etmektedir.…”