Background: Although rare, cardiac arrest during pregnancy is the leading cause of maternal death. Recently, its incidence has been increasing worldwide because more pregnant women have risk factors. The provision of early, high-quality cardiopulmonary resuscitation (CPR) plays a major role in the increased likelihood of survival; therefore, clinicians should be familiar with its management. Due to the aortocaval compression caused by the gravid uterus, clinical guidelines often emphasise the importance of maternal positioning during CPR, but there has been little evidence regarding which position is most effective.Methods: We searched the Cochrane Central Register of Controlled Trials, MEDLINE, Embase, and OpenGrey (updated on April 3, 2021). We included clinical trials and observational studies with reported outcomes related to successful resuscitations. Results: We included eight studies out of the 1,490 screened. All of these were simulation-based cross-over randomised controlled trials examining the quality of chest compressions. No data were available about the survival rates of mothers or fetuses/neonates. Meta-analyses indicated that resuscitation of pregnant women in the 27°–30° left-lateral tilt position lowered the quality of chest compressions, and the rates of correct compression depth and correct hand position decreased by 17% and 9%, respectively when compared with resuscitation in the supine position. Inexperienced clinicians faced difficulties in performing chest compressions in the left-lateral tilt position. Conclusions: Given that manual left uterine displacement allows the patient to remain supine, the resuscitation of women in the supine position using manual left uterine displacement should continue to be supported. Further research is needed to fill knowledge gaps regarding the effects of maternal positioning on clinical outcomes, such as survival rates following maternal cardiac arrest.