Coronary events in Khartoum, Sudan

Khalil, Siddiq Ibrahim; Ibrahim-Khalil, Mohammed; Hag, Mohammed El; Shafie, Sohaib El; Mahgoub, Fatih; Ali, El Nagi M.

doi:10.1016/0895-4356(96)00116-3

Cited by 6 publications

(6 citation statements)

References 8 publications

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“…Khalil et al showed that coronary event rate for men and women was 112/100,000 in Khartoum in 1989 [ 14 ]. Khalil et al used the diagnostic and classification criteria of the World Health Organization Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA) project.…”

Section: Discussionmentioning

confidence: 99%

Prevalence and Risk Factors for Acute Coronary Syndrome Among Sudanese Individuals With Diabetes: A Population-Based Study

et al. 2017

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BackgroundAcute coronary syndrome (ACS) is common with diabetes. The aim of this study was to establish prevalence and risk factors for ACS among Sudanese individuals with diabetes mellitus (DM).MethodsA descriptive cross-sectional study was conducted in Khartoum State and Atabra (North of Sudan). The data collection was performed through pretested questionnaire, in addition to measurement of lipid profile and HbA1c.ResultsAmong the 496 respondents, 234 (48.4%) were males and only 15 of them had ACS, while 255 (51.6%) were females and 12 had ACS. Therefore, the prevalence of ACS was 5.44% (95% confidence interval (CI): 3.45-7.44%). The unadjusted risk factors for ACS were age (P = 0.0008864), duration of DM (P = 0.01105) and presence of hypertension (P = 0.0006021). The presence of albuminuria, gender, and body mass index (BMI) was not associated with ACS. In addition, parameters like HbA1c, high-density lipoprotein (HDL), triglyceride and low-density cholesterol (LDL) were also not associated with ACS. Logistic regression analysis showed that duration of diabetes (odds ratio (OR) for below 5 years’ history of DM = 0.175 (95% CI for OR: 0.180 - 0.835), P = 0.04051) and hypertension (OR = 2.462 (95% CI for OR: 1.007 - 6.500), P = 0.039) were absolute risk factors for ACS.ConclusionThe prevalence of ACS is estimated to be 5.44%. ACS in Sudanese individuals with DM was associated with hypertension, increase in age and increase in duration of DM.

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Section: Discussionmentioning

confidence: 99%

Prevalence and Risk Factors for Acute Coronary Syndrome Among Sudanese Individuals With Diabetes: A Population-Based Study

et al. 2017

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“…There has been only one population-based study in Sudan, conducted by Khalil et al ., which addressed the issue of coronary event rates 36. All coronary events occurring in Khartoum, capital of Sudan, were registered during the calendar year 1989 using the diagnostic and classification criteria of the World Health Organisation Monitoring of Trends and Determinants in Cardiovascular Disease (MONICA) project 37.…”

Section: Atherosclerotic Heart Diseases and Risk Factorsmentioning

confidence: 99%

The state of heart disease in Sudan : review article

Suliman¹

2011

CardioVascular Journal of Africa

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Cardiovascular disease (CVD) is the leading cause of mortality worldwide and an important cause of disability. In Africa, the burden of CVD is increasing rapidly and it is now a public health concern. Epidemiological data on diseases is scarce and fragmented on the continent.AimTo review available data on the epidemiology and pattern of heart disease in Sudan.MethodsData were obtained from the Sudan Household Survey (SHHS) 2006, annual health statistical reports of the Sudan Federal Ministry of Health, the STEPS survey of chronic disease risk factors in Sudan/Khartoum, and journal publications.ResultsThe SHHS reported a prevalence of 2.5% for heart disease. Hypertensive heart disease (HHD), rheumatic heart disease (RHD), ischaemic heart disease (IHD) and cardiomyopathy constitute more than 80% of CVD in Sudan. Hypertension (HTN) had a prevalence of 20.1 and 20.4% in the SHHS and STEPS survey, respectively. There were poor control rates and a high prevalence of target-organ damage in the local studies. RHD prevalence data were available only for Khartoum state and the incidence has dropped from 3/1 000 people in the 1980s to 0.3% in 2003. There were no data on any other states. The coronary event rates in 1989 were 112/100 000 people, with a total mortality of 36/100 000. Prevalence rates of low physical activity, obesity, HTN, hypercholesterolaemia, diabetes and smoking were 86.8, 53.9, 23.6, 19.8, 19.2 and 12%, respectively, in the STEPS survey. Peripartum cardiomyopathy occurs at a rate of 1.5% of all deliveries. Congenital heart disease is prevalent in 0.2% of children.ConclusionHeart diseases are an important cause of morbidity and mortality in Sudan. The tetrad of hypertension, RHD, IHD and cardiomyopathy constitute the bulk of CVD. Hypertension is prevalent, with poor control rates. A decline in rheumatic heart disease was seen in the capital state and no data were available on other parts of the country. No recent data on IHD were available. Peripartum cardiomyopathy and congenital heart disease occur at similar rates to those in other African countries.

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“…The first reported prevalence of coronary heart disease (CHD) among cardiovascular disease (CVD) admissions was 12.6% in 1961 and slowly increased to 17.8% by 1984 2,3 . A population based report of coronary events in Khartoum (1996) reported an annual prevalence rate of 112/100 000 and a fatality rate of 36/100 00 4 . The pattern of CVD had shown major changes during the last three decades and noticeable increase in the rates of CHD was noted by many clinicians and government health authority 4,5 .…”

Section: Introductionmentioning

confidence: 99%

“…A population based report of coronary events in Khartoum (1996) reported an annual prevalence rate of 112/100 000 and a fatality rate of 36/100 00 4 . The pattern of CVD had shown major changes during the last three decades and noticeable increase in the rates of CHD was noted by many clinicians and government health authority 4,5 . A recent hospital based study of CV admissions in Al Shaab Hospital, a cardiac referral hospital in Khartoum, has shown HF accounted for 73% of admissions to coronary care unit.…”

Section: Introductionmentioning

confidence: 99%

Emergence of ischemic cardiomyopathy as the main cause of heart failure in urban Sudanese population

Khalil¹,

Khalil²,

Albadri³

et al. 2015

ICFJ

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Heart failure is a rapidly growing cardiovascular (CV) problem in Sudan due to affluence and lifestyle changes producing high rates of CV risk factors and consequent coronary heart disease in addition to the historical causes of hypertension and rheumatic heart disease.This study is intended to measure the prevalence of heart failure (HF) among hospital admissions and study the recent trends in etiology, clinical features and methods of treatment.Methods: All admissions at Sudan Heart Institute between January 2000 and June 2011 were studied. Patients went through detailed history taking and physical examination. Investigations included 12 lead ECG and chest X-ray, echocardiography and cardiac catheterization was also carried out where indicated.Results: A total of 12453 cases were collected and 1073 were verified by the authors and an independent cardiologist, constituting 8.6% of CV disease admissions. Female to male ratio was 1:1.6 and age 15 to 96 years (median 58 years). 74.6 % of all patients were urban dwellers. Left ventricular (LV) systolic dysfunction accounted for 71.6% and preserved systolic function 28.4%. Ischemic aetiology accounted for 44.6% of cases, hypertension 24.8 %, RHD 14.4% and idiopathic 12.4%. Conclusion: Ischemic cardiomyopathy emerged as the main cause of HF among urban population probably due to changes in lifestyle. Treatment and prevention of these risk may reduce the prevalence of heart failure.

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Coronary events in Khartoum, Sudan

Cited by 6 publications

References 8 publications

Prevalence and Risk Factors for Acute Coronary Syndrome Among Sudanese Individuals With Diabetes: A Population-Based Study

Prevalence and Risk Factors for Acute Coronary Syndrome Among Sudanese Individuals With Diabetes: A Population-Based Study

The state of heart disease in Sudan : review article

Emergence of ischemic cardiomyopathy as the main cause of heart failure in urban Sudanese population

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