Coronary CT Angiography Using Low Iodine Delivery Rate and Tube Voltage Determined by Body Mass Index: Superiority in Clinical Practice

Wang, Yüan; Qu, Tingting; Wang, Huijuan; Qu, Yuan; Niu, Gang; Yang, Jian

doi:10.1007/s11596-019-2112-5

Cited by 3 publications

(4 citation statements)

References 20 publications

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“…Yuan et al explored the feasibility of low tube voltage and IDR determined by patients' BMI in CCTA. 15 The protocol of 100 kVp and 1.3 gI/s was used with BMI on 18.5−24.9 kg/m 2 , and the patients of BMI ≥25 kg/m 2 were used with a protocol of 120 kVp and 1.6 gI/s. Li et al explored the use of 70 kVp tube voltage in patients with BMI less than 26 kg/m 2 .…”

Section: Discussionmentioning

confidence: 99%

“…[11][12][13] Efforts have also been made in optimizing the vessel enhancement in order to improve the image quality of CCTA. [14][15][16] Mihl et al evaluated a body weight adapted protocol for contrast injection, where a more homogeneous enhancement pattern was achieved between different weight groups while the volume of contrast media could be reduced for the majority of patients. 17 Andreini et al demonstrated the feasibility of using reduced iodine concentration and an 80 kVp tube voltage on patients with low body weight.…”

Section: Introductionmentioning

confidence: 99%

“…Efforts have also been made in optimizing the vessel enhancement in order to improve the image quality of CCTA 14–16 . Mihl et al.…”

Section: Introductionmentioning

confidence: 99%

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Refining the radiation and contrast medium dose in weight‐grouped scanning protocols for coronary CT angiography

Zhang,

Wang,

et al. 2023

J Applied Clin Med Phys

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To refine the currently used, weight-grouped protocol for coronary computed tomography angiography (CCTA), in terms of the radiation and contrast medium dose, through clinical evaluation. Methods: Following the current routine setting that varies between three weight groups (group A: 55-65 kg, group B: 66-75 kg, group C: 76-85 kg), three additional reduction protocols were proposed to each group, with different combinations of lowered tube voltage (70-100 kVp), tube current (100-220 mAs), and iodine delivery rate (0.8-1.5 gI/s). A total of 321 patients scheduled for CCTA due to suspected coronary artery disease were enrolled, who were randomly assigned to one of the four subgroups of settings under the corresponding weight group. The resulting objective image quality was compared by measuring the contrast-to-noise ratio and signal-to-noise ratio.Subjective image quality was graded by two radiologists using a 4-point Likert scale, on a total of 3848 segments. The optimal protocol for each weight group was determined with respect to the image quality and the applied radiation dose. Results: For all three groups, no significant difference was noticed in objective images quality between subgroups of dose settings (all p > 0.05). The average score on subjective image quality was ≥3 for every subgroup, while the percentage of score 4 showed greater dependence on the setting, ranging from 83.2% to 91.5%, and was chosen to be the determining factor. The optimal dose settings were found to be 80 kVp, 150 mAs, and 1.0 gI/s for patients of 55-75 kg in weight, and 100 kVp, 170 mAs, and 1.5 gI/s for those of 76-85 kg. Conclusion: It is feasible to refine the currently used, weight-grouped protocol for CCTA in terms of radiation and contrast medium dose, by use of an optimization strategy where the balance between dose and image quality can be improved in a routine clinical setting.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Refining the radiation and contrast medium dose in weight‐grouped scanning protocols for coronary CT angiography

Zhang,

Wang,

et al. 2023

J Applied Clin Med Phys

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“…ough side reactions are infrequent, the lower injection volume and speed could be safer. ere is a large body of literature suggesting that BMI could be the indicator to adjust the injection protocols [4,14]. us far, only a few studies have investigated the effect of BMI on vascular enhancement with the thirdgeneration DSCT under a single voltage.…”

Section: Discussionmentioning

confidence: 99%

Ladder‐Like Low Iodine Delivery Rate Injection Protocols Based on BMI at 70 KV by Automated Tube Voltage Selection in Coronary CTA

Shang

Zhu

Han

et al. 2022

Contrast Media & Molecular Imaging

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Objective. To evaluate the feasibility of reducing the injection velocity and volume of contrast agent according to BMI, and the effect of body weight (BW), body surface area（BSA）, body mass index（BMI），and blood volume (BV) on aortic contrast enhancement when the voltage of third-generation dual-source CT is selected at 70 KV. Methods. A total of 280 patients selected at 70 KV were randomly divided into an experimental group and a control group. Each group was divided into 7 subgroups according to BMI ≤20, 20–21, 21-22, 22-23, 23-24, 24-25, and 25–26. The experimental group uses 2.3/2.4/2.5/2.6/2.7/2.8/2.9 ml/s injection speed with 350 mgI/ml contrast agents according to the subgroups; injection time was fixed at 10 s. In the control group, the fixed injection flow rate was 3.5 ml/s, time was 12 s with a total of 42 ml. Subjects in both groups were inspected to adaptive prospective ECG-gating sequence scanning, and subjective and objective image quality of the two groups were compared using Student's t-test. BMI, BSA, and BV were calculated from the patient’s body weight and height. We assess the relationship between aortic attenuation and BW, BMI, BV, and BSA using regression analysis or correlation analysis. Results. Significant differences exist in vascular enhancement between the two groups; SNR and CNR of objective image quality in the experimental group were lower than those in the control group ( P < 0.05). Both groups had the same subjective image scores ( P > 0.05). The number of vessels in the optimal enhancement range counts more in the experimental group than in the control group (χ2 value = 334.25, P ＜ 0.05). In the control group, a weak to medium correlation was seen between vascular enhancement and BMI (r = −0.20), BW (r = −0.42), BSA (r = −0.46), and BV (r = −0.48) ( P ＜ 0.05 for all). Conclusions. Compared to BW, BSA, and BV, a weaker negative correlation exists between vascular enhancement and BMI when ATVS selects 70 KV. However, as a much easier way to operate, the stepped low flow and low-contrast agent injection based on BMI was feasible, and the image quality was more homogenized than that of the control group.

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Recommandations du CIRTACI sur l’optimisation de l’injection des produits de contraste iodé en tomodensitométrie – Explorations vasculaires

Gaultier¹,

Mandry²,

Pontana³

et al. 2020

Journal d'imagerie diagnostique et interventionnelle

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Coronary CT Angiography Using Low Iodine Delivery Rate and Tube Voltage Determined by Body Mass Index: Superiority in Clinical Practice

Cited by 3 publications

References 20 publications

Refining the radiation and contrast medium dose in weight‐grouped scanning protocols for coronary CT angiography

Refining the radiation and contrast medium dose in weight‐grouped scanning protocols for coronary CT angiography

Ladder‐Like Low Iodine Delivery Rate Injection Protocols Based on BMI at 70 KV by Automated Tube Voltage Selection in Coronary CTA

Recommandations du CIRTACI sur l’optimisation de l’injection des produits de contraste iodé en tomodensitométrie – Explorations vasculaires

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