Coronary Artery Disease in South Asians

Abstract

It is well established that South Asians living in the western world have a higher burden of cardiovascular disease than other ethnicities. Additionally, South Asians develop cardiovascular disease at a younger age, have a more aggressive form of coronary artery disease, and a higher overall mortality. This predilection seems to be multifactorial and includes a combination of traditional and emerging risk factors with an absence of ethnic-specific prevention and control measures. Future direction points toward ongoing research with the aim of discovering technology for earlier detection. Additionally, coronary artery disease in South Asians could be addressed by increasing awareness, modifying health beliefs through health-promotion strategies, and instituting ethnic-specific control measures including appropriate and early pharmacological intervention.

Prevalence and Correlates of Type D Personality among Survivors following Acute Myocardial Infarction in a Tertiary Care Center in South India

“…Ethnically, South Asians have a higher vulnerability to CAD. 19 Further, there is robust evidence linking Type D personality with adverse outcomes following CAD independent of several known risk factors such as hypertension and disease severity. 44 Taken together with our findings, we recommend further investigation of the potential etiological contribution of Type D personality in causation of MI.…”

“…15 16 17 However, there have been some conflicting reports too which suggested no association between Type D personality and absolute incident CHD risk among older adults without clinical features of CHD at intake. 18 Given the strength of evidence linking Type D personality to poor outcomes in CHD, the availability of a short and convenient instrument to measure Type D scale (DS-14), and the high prevalence and more aggressive nature of CHD among ethnic South Asians, 19 there seems to be a compelling case to study the prevalence and determinants of Type D among Indians with CHD about which there is little literature so far. This would give vital information about the extent of influence of personality, which may presumably vary across cultures, on CHD in the Indian setting.…”

The Role of Physical Activity Prescription in Cardiovascular Disease Prevention Amongst South Asian Canadians

“…Therefore, such beliefs may partly explain the low PA participation levels ( 36 ). Additionally, previous work has shown that South Asians' beliefs and attitudes have a significant effect on health outcomes, as health beliefs influence health behavior, such as a lower locus of control being associated with an increased risk of MI occurrence ( 47 – 49 ). To combat this issue, modifying illness perception is important to ensure that these individuals believe they have capacity to improve their cardiovascular health ( 50 ).…”

“…Accordingly, the aforementioned TDF may be used to identify more specific barriers and facilitators that physicians may face with PA prescription, such that interventions may be designed with the intent of targeting these barriers, making the intervention workshops more efficacious ( 111 , 122 , 123 ). Nonetheless, these workshops should (1) emphasize the importance of the cultural sensitivity in PA prescription for SACs and (2) recognize the sociocultural context of SACs' CVD risk; knowledge of these sociocultural variations may help to facilitate the delivery of PA programs that satisfy the cultural preferences of SACs, and ultimately enhance uptake and utilization ( 83 ), and also improve quality of care ( 49 ).…”

Effects of trimetazidine on ventricular remodeling in coronary artery disease patients with left ventricular hypertrophy: the rationale and design of a randomized controlled trial

“…Coronary artery disease (CAD) has become the second leading cause of death after malignant tumor in China, with the prevalence of 6.46% [1,2]. Left ventricular hypertrophy (LVH), an increase in muscle mass of left ventricle, has been identified as a powerful risk factor for future cardiovascular morbidity and mortality, with the risk of cardiovascular events increasing six-fold to eightfold [3].…”