Coronary artery disease in patients with peripheral artery disease

Prediction of Coronary Artery Disease in Patients With Lower Extremity Peripheral Artery Disease

“…14) Another study demonstrated that hypertension and diabetes could predict the presence of CAD and multi-vessel CAD in PAD patients. 15) Taken together, previous publications and our data indicate that diabetes was the only common factor to predict CAD in patients with lower extremity PAD. Therefore, screening of CAD should be considered in PAD patients with diabetes.…”

“…The patients with multi-vessel CAD had more cardiovascular risk factors than those with normal, minimal and single CAD in our study and a similar result was observed in a previous study. 15) In this study, disease location in the lower extremities revealed that a femoral-popliteal lesion was the most common (41%), followed by an aortic-iliac location in 23%, and a below knee location in 2% as a single lesion, and others were combined multi-level PAD (34%). Similarly, Diehm, et al reported that target lesion location was in the femoral-popliteal region in 51.2%, iliac region in 27.7%, and the infragenicular region in 21.1% in patients who underwent an endovascular procedure of lower extremity arteries.…”

“…[11][12][13] However, the predictive value of conventional cardiovascular risk factors for CAD in patients with PAD varies in previous studies. 14,15) Thus, novel predictors other than conventional cardiovascular risk factors are necessary for prediction of CAD in patients with PAD. Previous studies showed that the location of the lesion is associated with survival in patients with lower extremity PAD.…”

Diagnosis and Management of Cardiovascular Disease in Advanced and End‐Stage Renal Disease

“…It is important to identify prognostically important CAD that may require revascularization prior to transplantation 37. Evidence of atherosclerotic vascular disease involving other vascular beds, particularly peripheral arterial disease, may help identify patients with advanced coronary atherosclerosis 38, 39, 40, 41. Since peripheral arterial disease is highly associated with CAD, it may be reasonable to pursue left heart catheterization in patients with peripheral arterial disease despite negative stress tests.…”

Computed tomography characteristics of coronary artery atherosclerosis in subjects with lower extremity peripheral artery disease and no cardiac symptoms

“…A multiphase reconstruction invasive coronary angiography, which showed that even >70% of subjects with PAD may have CAD. 7 Recently, computed tomography coronary angiography (CTCA) has emerged as a new imaging modality, which enables noninvasive evaluation of coronary artery atherosclerosis. 8 Currently, the European Society of Cardiology guidelines on the management of coronary artery disease has clarified the role of CTCA to detect CAD in subjects with low intermediate pretest probability of the disease.…”