Coronary Artery Aneurysm

The Levels of Asymmetric Dimethylarginine in Patients with Isolated Coronary Artery Ectasia

“…Although it has been suggested that ectasia is commonly a variant of obstructive CAD, its pathogenesis remains poorly understood (1,2,17). Coronary flow in aneurysmal segments is impaired even in the absence of obstructive disease.…”

“…Coronary artery ectasia (CAE) has been defined as localized or diffuse dilation of the coronary arteries exceeding the 1.5 fold of normal adjacent segment in coronary angiography (1,2). Prevalence of CAE appears to rise in recent years (3).…”

Coronary Artery Aneurysms: An Update

“…Atherosclerosis is the most common etiology in the U.S., and Kawasaki disease is the most common etiology in the Far East (Cohen & Ogara, 2008). Atherosclerosis is responsible for more than 50% of CAAs in adults in the Western world, whereas Kawasaki disease, which is characterized by an acute, self-limited vasculitis occurring in childhood, may lead to the development of CAAs in 15 to 25% of untreated children (Falsetti & Carrol, 1976;Pahlavan & Niroomand, 2006). Other causes of CAAs include inflammatory arterial diseases (polyarteritis nodosa, syphilis, Takayasu arteritis, Behçet´s disease), connective tissue disorders (systemic lupus erythematosus, rheumatoid arthritis, ankylosing spondylitis, scleroderma), hereditary collagen defects (Marfan syndrome, Ehlers-Danlos syndrome), coronary artery revascularization procedures (balloon angioplasty and laser atherectomy), candidiasis, chest traumas, and primary hyperaldosteronism (Alford et al, 1976;Antoniadis et al, 2008).…”

Chronic Fluoride Exposure Has a Role in Etiology of Coronary Artery Ectasia: Sialic Acid/Glycosaminoglycan Ratio

“…Coronary angiograms were analyzed by two blinded interventional cardiologists without knowledge of the clinical status and laboratory measurements of the subjects. CAE was defined as the segmental or diffuse dilation of the coronary arteries to >1.5-fold the diameter of the adjacent segments of the same artery or of different arteries as defined by Falsetti and Carroll [15]. We used this definition for terminology.…”