Cornell Medical Index as a health measure in epidemiological studies. A test of the validity of a health questionnaire.

Abramson, J. H.; Terespolsky, L; Brook, Jeff; Kark, Sidney L.

doi:10.1136/jech.19.3.103

Cited by 31 publications

(17 citation statements)

References 13 publications

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“…Often, occasionally, never." There were also 8 questions from the Cornell Medical Index (CMI) that covered anxiety, 25 for example, "Do you ever become nervous or agitated? Are you ever keyed up and jittery?"…”

Section: Methodsmentioning

confidence: 99%

Cortisol, Testosterone, and Coronary Heart Disease

et al. 2005

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Background-There is a popular belief that chronic stress causes heart disease through psychoneuroendocrine mechanisms. We have examined whether an elevated circulating cortisol-to-testosterone ratio increases the risk of ischemic heart disease. Methods and Results-We undertook a prospective cohort study of 2512 men aged 45 to 59 years between 1979 and 1983 from Caerphilly, South Wales, with a mean follow-up of 16.5 years. Subjects underwent a clinical examination, and morning fasting blood samples were taken for analysis of cortisol levels, testosterone levels, and other cardiovascular risk factors. The ratio of cortisol to testosterone showed weak associations with potential confounding factors but strong positive associations with components of the insulin resistance syndrome (PϽ0.001). A positive linear trend was seen across quintiles of cortisol:testosterone ratio for incident ischemic heart disease (age-adjusted OR per z score change in ratio 1.22, 95% CI 1.07 to 1.38, Pϭ0.003). This was markedly attenuated after adjustment for components of the insulin resistance syndrome (age-adjusted OR per z score change in ratio 1.10, 95% CI 0.96 to 1.25, Pϭ0.18). There was no association between the cortisol:testosterone ratio and other causes of death (age-adjusted hazard ratio 0.99, 95% CI 0.88 to 1.11, Pϭ0.81). Conclusions-This is the first population-based prospective study that has found a specific association between cortisol:testosterone ratio and incident ischemic heart disease, apparently mediated through the insulin resistance syndrome. Whether this reflects the effects of chronic stress, behavioral factors, or genetic influences remains to be determined. (Circulation. 2005;112:332-340.)

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Section: Methodsmentioning

confidence: 99%

Cortisol, Testosterone, and Coronary Heart Disease

et al. 2005

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“…In general, a positive response to more than 30 questions on the CMI is indicative of emotional illhealth (Brodman et al, 1952;Abramson et al, 1965). In screening job applicants at a cigarette factory, Erdmann et al (1953) found that 4% of 201 women and none of 205 men answered 30 or more questions affirmatively.…”

Section: Discussionmentioning

confidence: 99%

The Cornell medical index in disability evaluation.

Stout¹,

Wight²,

Bruhn³

1969

Journal of Epidemiology & Community Health

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“…In addition, this questionary contained two series of 10 questions in random order. One series related to symptoms or signs commonly believed to occur in iron-deficiency anaemia; the other 10 were similar to questions in the Cornell Medical Index which have been used in community studies of psychoneurosis by Rawnsley (1966), Abramson, Terespolsky, Brook, and Kark (1965), and others. These latter questions were used here to give a measure of psychoneurosis in each subject.…”

Section: Methodsmentioning

confidence: 96%

Evaluation of a screening survey for anaemia in adult non-pregnant women.

Elwood¹,

Waters²,

Greene³

et al. 1967

BMJ

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Regional Ileitis-Feldman et al. and the central problem of whether primary psychosomatic disease exists. Nevertheless the significant emotional factors relating to psychosomatic illness noted in the literature were investigated and found not to apply to any important degree. We do, therefore, raise the question whether the disease should be regarded as psychosomatic in any way.BIBLIOGRAPHY Acheson, E. D. (1960). Gut, 1, 291. (1965). Chapter 11 in Badenocb and Brooke (1965). and Nefzger, M. D (1963). Gastroenrerology, 44, 7. Arieti, S (1959). American Hanabook of Psychiatry. New York.Armitage, G., and Wilson, M. (1950) Brit. 7. Surg., 38, 182. Atwell, J. D., Duthie, H. L., and Goligher, J. C. (1965). Ibid., 52, 966. Aylett, S. 0. (1966). Brit. med. 7., 1, 1001. Badenoch. J., and Brooke, B. N. (1965). Recent Advances in Gastroenterology. Boston.Bahn, A. K., Gardner. E. A., Alltop, L., Knatterud, G. L., and Solomon, M. (1967). Amer. 7. publ. Hith, 56, 2033. Bargen, J A. (1955. Wis. med. 7., 54, 367. -(1966 Grace. W. J. (1953). Gastroenterology, 23, 542. Hendrix, T. (1964). Chapter 4 in Mellinkoff (1964). Hunt, T. (1965). Trans. med. Soc. Lond., 81, 87. Janowitz, H. D. (195). 7. Mt Sinai Hosp., 22, 223. Kaelbling, R., and Patterson, R. M. (1966 Brit. med. J'., 1967, 4,[714][715][716][717] Considerable interest has been shown recently in community health screening (Backett, 1960 ; Wilson, 1963 ;Acheson, 1963; Horne, Clark, and Patterson, 1967). The value of any healthscreening procedure depends both on the proportion of persons detected with the disease (or diseases) being sought, or with treatable associated conditions, and on the importance to life or health of these conditions. The number of affected persons detected is dependent both on the prevalence of the disease, or the conditions associated with it, in the community to which screening is offered, and on the nature and extent of selection, if any, of those members of that community who co-operate. In fact very little is known about the selection of persons who readily co-operate in health-screening procedures except in a very few situations, such as mass miniature radiography (Bradbury, 1948) and cervical cytology (Wakefield and Bari6, 1965), in both of which it seems that affected individuals are, on average, less likely to co-operate than those who are unaffected, though in coal-workers' pneumoconiosis (Cochrane, 1951) and possibly in other compensatable industrial diseases the reverse is probably true. Other than in a few such cases very little is known about how persons who spontaneously attend community screening clinics differ from other members of the community.Assessment of the importance of the conditions detected during a screening survey necessitates value judgements which are not easily made and which ideally should be based on data relating to changes in the subsequent mortality or morbidity in the community screened. In the haematological community study described here the initial survey was evaluated as an ad hoc health-scree...

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Cornell Medical Index as a health measure in epidemiological studies. A test of the validity of a health questionnaire.

Cited by 31 publications

References 13 publications

Cortisol, Testosterone, and Coronary Heart Disease

Cortisol, Testosterone, and Coronary Heart Disease

The Cornell medical index in disability evaluation.

Evaluation of a screening survey for anaemia in adult non-pregnant women.

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