Corneal specular microscopy in infectious and noninfectious uveitis

Oliveira, Filipe de; Motta, Ana Carolina de Oliveira; Muccioli, Cristina

doi:10.1590/s0004-27492009000400006

Cited by 22 publications

(17 citation statements)

References 16 publications

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“…Endothelial anomalies have been observed in cases of AU and posterior uveitis. Some authors have studied these changes in several corneal disorders and uveitis, using specular microscopy (2) . It is well known that endothelial anomalies occur in uveitis (5) .…”

Section: Discussionmentioning

confidence: 99%

“…Although, in general, it is a smaller threat to vision than posterior uveitis, it is an important cause of blindness and ocular morbidity in Brazil (1,2) . Most often, AAU manifests with varying degrees of pain and ocular hyperemia, visual blurring, and inflammatory cells in the anterior chamber (AC).…”

Section: Introductionmentioning

confidence: 99%

“…Open-angle or closed-angle glaucoma have been described in 20% uveitis cases (3) , and ocular hypertension is considered an important complication of uveitis, particularly when it involves the anterior ocular segment (4) . The corneal involvement during uveitis remains understudied, although the cornea is probably a target of intraocular inflammation (2) . Inflammation of the anterior segment causes changes in the endothelium that, if severe, can compromise the integrity of the cornea; these changes have been observed in some studies using specular microscopy (5) .…”

Section: Introductionmentioning

confidence: 99%

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Anterior segment optical coherence tomography in acute anterior uveitis

Agra¹,

Agra²,

DANTAS³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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Purpose: To analyze the corneal thickness and anterior chamber (AC) angle using anterior segment optical coherence tomography (AS-OCT) in patients with acute anterior uveitis (AAU). Methods: Twenty two patients (24 eyes) were included. All patients underwent complete ophthalmological examination, applanation tonometry and AS-OCT at diagnosis and fifteen days after treatment. Results: Average corneal thickness before treatment was 564.2 ± 44.2 µm, 580.0 ± 44.3 µm and 580.1 ± 2.9 µm, respectively in central, pericentral and paracentral cornea. Fifteen days after treatment a significant decrease of corneal thickness was observed, with 529.5 ± 33.1 µm (p=0.0091) and 542.6 ± 33.6 µm (p=0.0068), respectively in central and pericentral cornea; paracentral corneal thickness (557.8 ± 35.3 µm) thinning did not reach statistical significance (p=0.1253). There was no significant change in temporal AC angle between visits, 44.3 ± 14.4 degrees before treatment and 44.7 ± 14.7 degrees fifteen days after (p=0.9343), and mean intraocular pressure, 10.8 ± 4.5 mmHg before treatment and 12.3 ± 3.0 mmHg fifteen days after (p=0.1874). Conclusion: In the studied group, AS-OCT detected a decrease of corneal thickness after AAU treatment. Temporal AC angle and intraocular pressure did not change during the studied period. Keywords

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Anterior segment optical coherence tomography in acute anterior uveitis

Agra¹,

Agra²,

DANTAS³

et al. 2014

Arquivos Brasileiros De Oftalmologia

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“…Based on the article published with the title of Corneal specular microscopy in infectious and noninfectious uveitis (1) , some brief comments about the specular microscope and the methodology used must be made.…”

mentioning

confidence: 99%

“…Binder et al suggested the inclusion of all cells of at least three images of the central and paracentral regions (6) . These four references are mentioned by McCarey et al in the article named Review of corneal endothelial specular microscopy for FDA clinical trial of refractive procedures, surgical devices, and new intraocular drugs and solutions (7) using as reference the article now being mentioned (1) . The use of 10 to 20 cells, as recommended by the equipment manual instructions, is reckless, as this manual must have been written over two decades ago.…”

mentioning

confidence: 99%