Corneal sensitivity in patients with leprosy and in controls.

Hieselaar, Laetitia Cjm; Hogeweg, M; Vries, C. L. De

doi:10.1136/bjo.79.11.993

Cited by 12 publications

(8 citation statements)

References 10 publications

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“…In human medicine esthesiometry is a valuable diagnostic tool to diagnose or to monitor progress of different eye diseases, to follow up healing after surgical treatments, to control compatibility of contact lenses, to diagnose neurologic diseases, to recognize early diabetic polyneuropathy and to recognize side effects of drugs 20,25–41 . Eye diseases in humans with accompanying decrease of corneal sensitivity are viral, bacterial and parasitic keratitis, keratoconjunctivitis sicca, corneal erosion and ulceration, chemical burns, corneal perforation, corneal scar formation, corneal dystrophy, glaucoma, and diabetic polyneuropathy 18,20,25,28,33,37,41,42 .…”

Section: Discussionmentioning

confidence: 99%

“…14,[17][18][19][20][21][22][23][24] In human medicine esthesiometry is a valuable diagnostic tool to diagnose or to monitor progress of different eye diseases, to follow up healing after surgical treatments, to control compatibility of contact lenses, to diagnose neurologic diseases, to recognize early diabetic polyneuropathy and to recognize side effects of drugs. 20,[25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41] Eye diseases in humans with accompanying decrease of corneal sensitivity are viral, bacterial and parasitic keratitis, keratoconjunctivitis sicca, corneal erosion and ulceration, chemical burns, corneal perforation, corneal scar formation, corneal dystrophy, glaucoma, and diabetic Table 1. Mean CTT ± SD and median CTT (in mm filament length) of the five prescribed corneal regions in 50 horses (n = 100 eyes) and in relation to age (3 age groups: 1-4 years, 5-10 years, > 10 years), gender (male/female), and side (right/left eye) of the horses polyneuropathy.…”

Section: Discussionmentioning

confidence: 99%

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Corneal esthesiometry in the healthy horse

Kaps

Richter

Spiess

2003

Veterinary Ophthalmology

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Corneal esthesiometry in the healthy horse

Kaps

Richter

Spiess

2003

Veterinary Ophthalmology

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“…Physiologic conditions consist of aging, menstrual cycle, pregnancy and defective lid closure . Pathologic conditions consist of diabetes, myasthenia gravis, leprosy, chronic inflammation, infection, corneal dystrophies, persistence of dry eye, keratoconus and trachoma …”

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confidence: 99%

Normal corneal sensitivity and its changes with age in Tehran, Iran

mirzajan

Khezri

Jafarzadehpur

et al. 2015

Clinical and Experimental Optometry

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Background: The present study sets out to determine normal corneal sensitivity in five corneal regions and its changes with age in an Iranian population. Methods: The corneal sensitivity of the centre of the cornea and at four corneal regions, namely, nasal, inferior, temporal and superior at 2.0 mm from the limbus of the right eye of 596 subjects aged 15 to 81 were measured using a Cochet-Bonnet aesthesiometer. All measurements were performed by the same examiner at 18 degrees centigrade and 35 per cent humidity between 2:00 and 5:00 pm. The subjects were divided into six age groups of 15 to 25 years, 26 to 35, 36 to 45, 46 to 55, 56 to 65 and over 65 years, respectively. Since the measurement outcomes were not continuous, the data was analysed using non-parametric statistics. Results:The frequency of corneal sensitivity of 60 mm in all corneal regions was decreased with advancing age after 35 years (χ 2 p < 0.001). The strongest correlation between age and corneal sensitivity was for the centre of the cornea (-0.52), followed by nasal (-0.49), temporal (-0.48), inferior (-0.47) and superior (-0.46) regions of the cornea, which had significant negative correlations (p < 0.001). The five different corneal regions showed significant differences of corneal sensitivity (p < 0.001). In different age groups, the difference was seen in the three lower age groups of 1, 2 and 3, while in the three older age groups of 4, 5 and 6, there were no differences in corneal sensitivity among five corneal regions (p > 0.05). Conclusion: Based on the findings of the current study, all regions of the cornea showed a faster reduction in sensitivity with age in this sunny environment compared to the results of previous studies.

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“…9 Beberapa laporan publikasi menyatakan bahwa hilangnya sensasi kornea dapat terjadi akibat kombinasi reaksi kusta tipe I dan II, facial palsy atau pada pasien lepromatosa. 17 Derajat kerusakan kornea akibat pajanan sangat bergantung pada: (1) derajat kelemahan orbikularis, (2) sensasi kornea, (3) jumlah sekresi musin dan meibom; dan (4) reflek berkedip. 20 Keratitis dapat meninggalkan jaringan parut halus yang disebut nebula dan jaringan parut tebal yang disebut leukoma.…”

Section: Kelainan Pada Kornea Mataunclassified

Kelainan Mata Pada Pasien Kusta

Sari¹

2019

MDVI

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ABSTRAKKeterlibatan intraokular paling sering terjadi pada kusta lepromatosa, dan tidak pernah pada kusta tuberkuloid. Tanda kelainan intraokular juga tidak umum didapati pada empat atau lima tahun pertama perjalanan penyakit. Kelainan mata pada kusta terjadi akibat kerusakan saraf dan invasi basil secara langsung. Komplikasi mata akibat kusta hanya terjadi pada segmen anterior dan adneksa mata. Lesi yang berpotensi menyebabkan kebutaan pada pasien kusta adalah lagoftalmus, hipoestesia kornea, iritis, skleritis dan atrofi iris. Riwayat atau sedang mengalami reaksi kusta tipe II dengan atau tanpa iritis, bercak di pipi atau infiltrasi difus di kulit wajah, pasien yang memiliki kecacatan tingkat I-II atau hanya pada mata, dan adanya penyakit penyerta, misalnya diabetes melitus atau glaukoma juga menjadi faktor risiko terjadinya kebutaan pada pasien kusta. Komplikasi mata juga sering ditemukan pada pasien kusta yang baru terdiagnosis dan yang sedang menjalani pengobatan. Deteksi dini, pengobatan yang efektif dan pengendalian reaksi yang tepat penting untuk menurunkan komplikasi mata pada pasien kusta.Kata kunci: kusta, kelainan mata, prevalensi, deteksi, pengobatan, pencegahan OCULAR ABNORMALITIES IN LEPROSY PATIENT ABSTRACTOcular involvement most commonly found in lepromatous leprosy and never in cases of tuberculoid leprosy. Signs of intraocular abnormality are not commonly found in the first four or five-years course of the disease. In 50% untreated multibacillary leprosy patients ocular lesions will appear at the end of the first decade. Ocular abnormalities in leprosy occurs due to nerve damage and direct invasion of bacilli. This complications due to leprosy occur only in the anterior segment and adnexa. Lesions that could potentially cause blindness in leprosy patients is lagophthalmus, corneal hypoaesthesia, iritis, scleritis and iris atrophy. A history or current episode of type II leprosy reaction with or without iritis, spots on the cheek or diffuse infiltration in the skin, patients who have a disability I-II level or only in the eye, and the presence of comorbidities such as diabetes mellitus or glaucoma is also risk factors of blindness in leprosy. Ocular complications are also commonly found in newly diagnosed leprosy patient and those undergoing treatment. Early detection, effective treatment and proper reaction management is important to reduce ocular complications in leprosy patients.

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Corneal sensitivity in patients with leprosy and in controls.

Cited by 12 publications

References 10 publications

Corneal esthesiometry in the healthy horse

Corneal esthesiometry in the healthy horse

Normal corneal sensitivity and its changes with age in Tehran, Iran

Kelainan Mata Pada Pasien Kusta

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