Corneal remodeling after implantation of a shape-changing inlay concurrent with myopic or hyperopic laser in situ keratomileusis

Steinert, Roger F.; Koch, Douglas D.; Cochener, Béatrice; Lang, Alan; Barragán-Garza, Enrique; Chayet, Arturo; Vargas, Luis G.

doi:10.1016/j.jcrs.2017.07.036

Cited by 3 publications

(2 citation statements)

References 8 publications

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“…The surgical placement of a corneal meniscus shaped inlay beneath a corneal flap alters the stroma anterior to the inlay to adopt predominately the inlay's shape (Lang et al, 2016). The epithelium remodels within a zone approximately twice the inlay diameter (Lang et al, 2016), with ~19 microns of central (~1 mm radius) central thinning regardless of the refractive error treated (Steinert et al, 2017). One disadvantage of the monocular approach of implanting inlays to increase the depth of focus of the visual system is the resulting anisocoria creates an imbalance in the retinal illuminances between the two eyes.…”

Section: Inlaysmentioning

confidence: 99%

Presbyopia: Effectiveness of correction strategies

Wolffsohn

Davies

2019

Progress in Retinal and Eye Research

216

178

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Presbyopia is a global problem affecting over a billion people worldwide. The prevalence of unmanaged presbyopia is as high as 50% of those over 50 years of age in developing world populations, due to a lack of awareness and accessibility to affordable treatment, and is even as high as 34% in developed countries. Definitions of presbyopia are inconsistent and varied, so we propose a redefinition that states "presbyopia occurs when the physiologically normal age-related reduction in the eye's focusing range reaches a point, when optimally corrected for distance vision, that the clarity of vision at near is insufficient to satisfy an individual's requirements". Strategies for correcting presbyopia include separate optical devices located in front of the visual system (reading glasses) or a change in the direction of gaze to view through optical zones of different optical powers (bifocal, trifocal or progressive addition spectacle lenses), monovision (with contact lenses, intraocular lenses, laser refractive surgery and corneal collagen shrinkage), simultaneous images (with contact lenses, intraocular lenses and corneal inlays), pinhole depth of focus expansion (with intraocular lenses, corneal inlays and pharmaceuticals), crystalline lens softening (with lasers or pharmaceuticals) or restored dynamics (with 'accommodating' intraocular lenses, scleral expansion techniques and ciliary muscle electrostimulation); these strategies may be applied differently to the two eyes to optimise the range of clear focus for an individual's task requirements and minimise adverse visual effects. However, none fully overcome presbyopia in all patients. While the restoration of natural accommodation or an equivalent remains elusive, guidance is given on presbyopic correction evaluation techniques.

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Section: Inlaysmentioning

confidence: 99%

Presbyopia: Effectiveness of correction strategies

Wolffsohn

Davies

2019

Progress in Retinal and Eye Research

216

178

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“…Thus, the clinical outcomes were the same between the LASIK groups, with differences less than 2 Snellen letters between the two groups. A limitation of this study is that the average SE ablation was +1.71 D for hyperopic treatment and -2.48 D for myopic treatment [10]. Whether or not this remodeling effect is consistent with higher levels of treatment has yet to be elucidated.…”

Section: Introductionmentioning

confidence: 88%

Corneal Remodeling to Correct Presbyopia: Mechanism of A Shape-Changing Corneal Inlay

Garza¹

2018

JOJO

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A new trifocal corneal inlay for presbyopia

Furlan

Montagud-Martínez

Ferrando

et al. 2021

Sci Rep

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Corneal inlays (CIs) are the most recent surgical procedure for the treatment of presbyopia in patients who want complete independence from the use of glasses or contact lenses. Although refractive surgery in presbyopic patients is mostly performed in combination with cataract surgery, when the implantation of an intraocular lens is not necessary, the option of CIs has the advantage of being minimally invasive. Current designs of CIs are, either: small aperture devices, or refractive devices, however, both methods do not have good performance simultaneously at intermediate and near distances in eyes that are unable to accommodate. In the present study, we propose the first design of a trifocal CI, allowing good vision, at the same time, at far, intermediate and near vision in presbyopic eyes. We first demonstrate the good performance of the new inlay in comparison with a commercially available CI by using optical design software. We next confirm experimentally the image forming capabilities of our proposal employing an adaptive optics based optical simulator. This new design also has a number of parameters that can be varied to make personalized trifocal CI, opening up a new avenue for the treatment of presbyopia.

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Corneal remodeling after implantation of a shape-changing inlay concurrent with myopic or hyperopic laser in situ keratomileusis

Abstract: After concurrent LASIK and inlay implantation, the visual acuity, induced add-power profile, and epithelial remodeling were the same, regardless of hyperopic or myopic treatment.

Cited by 3 publications

References 8 publications

Presbyopia: Effectiveness of correction strategies

Presbyopia: Effectiveness of correction strategies

Corneal Remodeling to Correct Presbyopia: Mechanism of A Shape-Changing Corneal Inlay

A new trifocal corneal inlay for presbyopia

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