Corneal Photoablation by Far Ultraviolet Lasers

Experimental corneal trephination has been achieved with the 193 nm argon fluoride excimer and 2.9 microns hydrogen fluoride and Er:YAG laser systems. Compared with metal blades and other lasers, the 193 nm excimer laser creates the best quality corneal excision, but has a relatively slow etch rate through the stroma, and its use requires toxic gas. The mid-infrared laser systems trephine the cornea in less than 10 seconds, but cause a 10 microns to 15 microns zone of adjacent stromal damage and create wounds that are approximately 2.5 times larger than wounds made by metal scalpels. The wavelength and laser pulse duration influence the cutting characteristics of the laser. Optical delivery systems using an axicon lens, a rotating slit, and a computer controlled scanning optical system have been developed for penetrating keratoplasty. Selection of the optimal laser system for penetrating keratoplasty must await further experimental studies. Refinements of the laser cavity and delivery system are necessary before clinical studies can begin. A carefully controlled randomized clinical trial comparing laser trephination with conventional mechanical trephines will be necessary to determine the safety and efficacy of a laser trephination system.

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Potential use of lasers for penetrating keratoplasty

Thompson

Barraquer

Parel

et al. 1989

Journal of Cataract and Refractive Surgery

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Laser Literature Watch

1987

Laser Medicine and Surgery News and Advances

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Corneal Photoablation by Far Ultraviolet Lasers

Cited by 2 publications

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Potential use of lasers for penetrating keratoplasty

Potential use of lasers for penetrating keratoplasty

Laser Literature Watch

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