Corneal Hysteresis and Intraocular Pressure Measurement in Children Using the Reichert Ocular Response Analyzer

Kirwan, Caitriona; O’Keefe, Michael; Lanigan, Bernadette

doi:10.1016/j.ajo.2006.07.058

Cited by 160 publications

(119 citation statements)

References 4 publications

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“…23 On the contrary, others found that CH and CRF are very independent of age. 24,25 Toubul et al 24 hypothesized that viscoelasticity still decreasing with age, because the CRF is positively correlated with IOP and because it is known that IOP increases with age, and thus CH and CRF variations are compensated with the IOP elevation. According to our data, CorVis ST was not capable of detecting age-related difference in normal population.…”

Section: Correlation Datamentioning

confidence: 99%

Repeatability of Ocular Biomechanical Data Measurements With a Scheimpflug-Based Noncontact Device on Normal Corneas

Németh¹,

Hassan²,

Csutak³

et al. 2013

J Refract Surg

115

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any of the instruments used in this study. Flattest and steepest keratometric data and also IOP showed highly significant correlation with the ten specific CorVis ST parameters. Conclusions:The novel technique measuring ocular biomechanical properties showed high repeatability for only IOP and pachymetric data determined in our study. Single measurements are not reliable in case of the ten device-specific parameters. The equipment allows for conducting clinical examinations, and screenings of surgeries altering ocular biomechanical properties with some form of averaging of multiple measurements.

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Section: Correlation Datamentioning

confidence: 99%

Repeatability of Ocular Biomechanical Data Measurements With a Scheimpflug-Based Noncontact Device on Normal Corneas

Németh¹,

Hassan²,

Csutak³

et al. 2013

J Refract Surg

115

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“…Existem importantes correlações entre as características geométricas e biomecânicas da córnea e estruturais do nervo óptico com outras características individuais, como sexo, idade, raça e pigmentação da íris (24)(25)(26)(27)(28)(29)(30)(31)(32)(33) . Um estudo realizado em olhos de cadáver falhou em identificar associações entre a espessura da córnea e da lâmina cribriforme, mas artefatos relacionados com a preservação provavelmente influenciaram nos resultados (34) .…”

Section: Discussionunclassified

“…Entretanto, novos estudos prospectivos podem ser realizados com maior cuidado na classificação racial dos pacientes. De fato, está bem estabelecido que existem diferenças significativas entre raças nos parâmetros corneanos e do nervo óptico, sendo que, na média, olhos de pacientes afro-americanos apresentam córneas mais delgadas e com propriedades biomecânicas mais baixas e nervos com maior diâmetro (24)(25)(26)(27)(28)(29)(30)(31)(32)(33) .…”

Section: Discussionunclassified

Estudo das correlações entre a área do disco óptico e as características geométricas e biomecânicas da córnea

Silva¹,

Silva²,

Lima³

et al. 2011

Rev. bras.oftalmol.

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RESUMOObjetivo: Correlacionar área do disco óptico com parâmetros geométricos e biomecânicos da córnea. Métodos: Estudo retrospectivo nos arquivos de pacientes do Instituto de Olhos Renato Ambrósio a fim de se identificar os pacientes que realizaram exames HRT (Heidelberg Retina Tomography), Pentacam e ORA. A retinografia digital foi revisada de modo a se classificar na escala DDLS (Disc Damage Likelihood Scale).Resultados: 244 olhos de 122 pacientes (75 mulheres) foram incluídos no estudo. A média de idade foi de 47,2 anos (de 8 a 97 anos, desvio padrão de 21,7). Não houve correlação significante entre área do disco e nenhuma das medidas de PIO (IOPg, IOPcc). Encontrou-se uma relação negativa significativa com CRF (r=-0,1337, p=0,0263). A relação com histerese foi também negativa (-0,1123), mas o valor p foi maior que 0,05 (0,0625). Não houve correlação significante entre área do disco e progressão paquimétrica mínima ou média. Entretanto, observou-se correlação significante e positiva entre a área do disco e astigmatismo corneano (Delta K), sendo de 1,15 (p=0,0129). Conclusão: Existe uma correlação negativa entre a área do disco óptico e os parâmetros biomecânicos e estruturais da córnea. Tal correlação pode ser parte da explicação da córnea ser um fator de risco para maior susceptibilidade do nervo óptico para neuropatia glaucomatosa.

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“…[21][22][23][24][25] In recent years, the Ocular Response Analyzer (ORA; Reichert, Inc., Buffalo, NY), an ocular instrument that can emit an air pulse directed to the corneal surface, has been used to dynamically measure the intraocular pressure (IOP) and investigate the corneal viscoelastic response. [26][27][28][29][30] Compared with the number of experimental studies, there is less theoretical work in these aspects. Glass et al 31 developed a simplified model to evaluate the corneal viscosity and elasticity in response to an air puff, but neither the nonlinearity of the corneal elastic properties nor the effect of corneal mass were taken into consideration.…”

Section: Discussionmentioning

confidence: 99%

Air Puff Induced Corneal Vibrations: Theoretical Simulations and Clinical Observations

Han¹,

Chen²,

Zhou³

et al. 2014

J Refract Surg

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PURPOSE: To investigate air puff induced corneal vibrations and their relationship to the intraocular pressure (IOP), viscoelasticity, mass, and elasticity of the cornea based on theoretical simulations and preliminary clinical observations. METHODS:To simulate the corneal movement during air puff deformation, a kinematic viscoelastic corneal model was developed involving the factors of corneal mass, damping coefficient, elasticity, and IOP. Different parameter values were taken to investigate how factors would affect the corneal movements. Two clinical ocular instruments, CorVis ST (Oculus Optikgeräte GmbH, Wetzlar, Germany) and the Ocular Response Analyzer (ORA; Reichert, Inc., Buffalo, NY), were employed to observe the corneal dynamical behaviors. RESULTS:Numerical results showed that during the air puff deformation, there would be vibrations along with the corneal deformation, and the damping viscoelastic response of the cornea had the potential to reduce the vibration amplitude. With consistent IOP, the overall vibration amplitude and inward motion depths were smaller with a stiffer cornea.CONCLUSIONS: A kinematic viscoelastic model of the cornea is presented to illustrate how the vibrations are associated with factors such as corneal mass, viscoelasticity, and IOP. Also, the predicted corneal vibrations during air puff deformation were confirmed by clinical observation.[J Refract Surg. 2014;30(3):208-213.]

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Corneal Hysteresis and Intraocular Pressure Measurement in Children Using the Reichert Ocular Response Analyzer

Cited by 160 publications

References 4 publications

Repeatability of Ocular Biomechanical Data Measurements With a Scheimpflug-Based Noncontact Device on Normal Corneas

Repeatability of Ocular Biomechanical Data Measurements With a Scheimpflug-Based Noncontact Device on Normal Corneas

Estudo das correlações entre a área do disco óptico e as características geométricas e biomecânicas da córnea

Air Puff Induced Corneal Vibrations: Theoretical Simulations and Clinical Observations

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