Corneal Endothelial Characteristics and Central Corneal Thickness in a Population of Turkish Cataract Patients

Goktas, Altan; Gümüş, Koray; Mirza, Galip Ertuğrul; Crockett, Charlene; Karaküçük, Sarper; Cavanagh, Harrison D

doi:10.1097/icl.0b013e318243e7d2

Cited by 15 publications

(16 citation statements)

References 19 publications

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“…Some studies have described “at-risk” endothelial cell densities as being less than 2000 cells/mm 2 [26, 27]. Some studies have showed the endothelial cell density of 1000 cells/mm 2 as the threshold for acceptable risk [28]. In this study population, the mean CD was 2454 ± 473.2 cells/mm 2 .…”

Section: Discussionmentioning

confidence: 72%

Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients

Liu

et al. 2017

Journal of Ophthalmology

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Purpose To describe corneal endothelial characteristics, central corneal thickness, and intraocular pressure in a population of Chinese age-related cataract patients and to determine the effects of age, gender, hypertension, and body mass index (BMI). Methods 1551 eyes were examined preoperatively. The parameters measured were endothelial cell density (CD), average cell area (CA), coefficient of variation (CV), cell hexagonality (HEX), central corneal thickness (CCT), intraocular pressure (IOP), and axial length (AL). Results There were significant differences in CV and BMI between genders. There was a significant decrease in CD, CCT, and IOP and, conversely, an increase in CA and BMI with increasing age. The patients who suffered from hypertension had bigger CA, less CD, and lower HEX than the patients who did not suffer from hypertension. CD has a negative correlation with age and CV and a positive correlation with CCT, CCT has a positive association with CD and IOP, and IOP had a negative relationship with age and a positive relationship with CCT, CA, and HEX. Conclusions Normative data for the corneal endothelium, central corneal thickness, and intraocular pressure in the normal age-related cataract patients are reported which will serve as a baseline for comparative studies about cataract.

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Section: Discussionmentioning

confidence: 72%

Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients

Liu

et al. 2017

Journal of Ophthalmology

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“…44 yaş üstü bireylerde ortalama 2258 hücre/mm 2 dü-zeyinde bulmuşlardır. 25 Bu çalışmaya göre çalışma-mızdaki ortalama endotel hücre yoğunluğu daha yüksektir.…”

Section: 23unclassified

“…26 Literatürde yaş arttıkça farklı oranlarda endotel hücre yoğunluğu düşüşleri bildirilmiştir. 24,25 Çalışmamızda da endotel hücre yoğunluğu ile zayıf da olsa negatif korelasyon saptanmıştır. Öte yandan, kornea endotel hücre yoğunluğunda PES'li hastalarda anlamlı düşüklük saptansa da hiçbir hastada postoperatif dönemde kalıcı kornea endotel yetmezliği ve kornea ödemi görülmediği kaydedildi.…”

Section: 23unclassified

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The Characteristics of Cornea Endothelium in Senile Cataract Patients with Pseudoexfoliation Syndrome

İlhan¹,

Türkoğlu²,

Bilgin³

et al. 2015

Turkiye Klinikleri J Ophthalmol

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“…Available data form these studies show statistically signi cant differences in endothelial cell parameters among ethnic groups and sexes. [1,[7][8][9][10][11][12][13][14] The differences in endothelial cell morphology among ethnic groups, age and sex show that normative data on the endothelial cell parameters may help assess the endothelial cell function in individual patients and could even further our understanding in corneal endothelial diseases.…”

Section: Introductionmentioning

confidence: 99%

Age-related changes of the corneal endothelium in a Hispanic elderly population.

Valdez-García¹,

Ortiz-Morales²,

Morales-Mancillas³

et al. 2020

Preprint

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Purpose: To assess the corneal endothelial morphometry in healthy elderly Hispanic eyes.Methods: A retrospective, cross-sectional, observational, descriptive, and analytical study was designed to assess by specular microscopy the central region of the corneal endothelium. In a 4-year period, a total of 75 eyes from 42 patients were studied. All eyes included were from patients 65 or older (mean: 73.87±6.86), without ocular disease or surgeries.Results: The mean cell density (MCD) was 2268±597.0 cells/mm2. 44% of patients had polymegethism, with an average coefficient of variation (CV) of 42.04 ± 10.1%. 76% of patients had low pleomorphism, with an average of 42.3 ± 8.9% hexagonal cells. The mean corneal thickness was 537±38.2 μm. There was no statistically significant difference between age groups for MCD, CV, hexagonality and pachymetry (p=>.05). 27% of patients had corneal guttata.Conclusion: This study suggests that the elderly Hispanic population has a high prevalence of polymegethism, pleomorphism and guttata. Surprisingly, the oldest age group (>85) had an above average MCD, low polymegethism and good pleomorphism.

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Corneal Endothelial Characteristics and Central Corneal Thickness in a Population of Turkish Cataract Patients

Abstract: The data from our study emphasize that age, but not gender, is the main determinant of ECD.

Cited by 15 publications

References 19 publications

Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients

Corneal Endothelial Characteristics, Central Corneal Thickness, and Intraocular Pressure in a Population of Chinese Age-Related Cataract Patients

The Characteristics of Cornea Endothelium in Senile Cataract Patients with Pseudoexfoliation Syndrome

Age-related changes of the corneal endothelium in a Hispanic elderly population.

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