Corneal Endothelial Changes in Correlation with Corneal Thickness after Phacoemulsification among Diabetic Patients

Abstract

Submit Manuscript | http://medcraveonline.com MethodsWe prospectively examined 23 eyes of each group of patients who were scheduled to have phacoemulsification surgery. Materials were collected from December 2016 till April 2017. Exclusion criteria were a history of previous ocular surgery or inflammation, abnormal findings by slit-lamp biomicroscopic examination, a small pupil diameter after a full dilation of less than 4.0 mm, and a preoperative endothelial cell density of less than 1500 cells/mm 2 . One surgeon performed all the surgeries. Specular microscopy was used on all eyes preoperatively, one week and one month postoperatively. Three photographs were taken per eye at each examination, and the mean of the measurements were calculated. The CCT (central corneal thickness), ECD (endothelial cell density), and CV (coefficient of variance) will be measured in all cases by automated analysis of the whole image. Complete medical history for type 2 diabetes based on medical history, blood glucose levels and HbA1c levels. Examination of visual acuity, subjective refraction, slit-lamp examination, IOP readings with applanation tonometry was done to all patients. Binocular indirect ophthalmoscopy was conducted for fundus examination.The density of the cataract was clinically graded by the same examiner on a scale of 1 to 6 using the Lens Opacities Classification system lll. IOL power and AC depth were recorded for all patients. A standardized stop and chop phacoemulsification technique was done with the phaco tip of 'white star Signature Pro®' Phaco-machine. Surgical techniques were conducted using retrobulbar anesthesia. Clear corneal incision was used with a 3.2 mm keratome. Sodium hyaluronate was injected to maintain the depth of the anterior chamber. Capsulorhexis completed using fine forceps. Hydro dissection was performed and the lens nucleus emulsified with Phaco machine using the stop and chop technique. The power used was 40-60%, a vacuum of 60-350 mmHg, and an aspiration flow rate of 25-30 ml/min. The bottle height raised to a maximum of 110 cm from a minimum of 90 cm during fragment removal. AbstractPurpose: We proposed to study the corneal endothelial change in correlation with corneal thickness after phacoemulsification with Intra Ocular Lens IOL implantation; comparing diabetics (long standing > 10 years) versus a control group of non-diabetics. These cataract patients were obtained from the Ophthalmology Clinic at Suez Canal University Hospital, Ismailia, Egypt. Aim:To determine how corneal endothelium in diabetic patients is affected by cataract surgery in comparison to age matched non-diabetics. This assessment will be made over the initial 1 month post-op period and will be determined (evaluated) by specular microscopy (model Nidek CEM 5301) as a primary report (Figure 1). Conclusion:Corneal endothelium in diabetic patients is more affected during the phacoemulsification for cataract extraction & IOL implantation surgery as evidenced in (one week) follow up post op. Comparison between pre-operat...

Comparison of corneal endothelial cell changes after phacoemulsification between type 2 diabetic and nondiabetic patients

“…Similar results were found in previous studies. Hugod et al [2] and Elbassiouny et al [26] reported that there were no differences in CCT between diabetic and nondiabetic patients after surgery. This is because there is ECD loss after cataract surgery, but this is not sufficient to affect corneal endothelial cell function.…”

“…Several studies have shown that diabetic patients may be more susceptible to corneal complications before and after intraocular surgery [6–26] . According to the reported results, after cataract surgery, the loss of ECD in diabetic patients was 5.95% to 29.07%, compared to 0.88% to 18.18% in healthy individuals [6–17] .…”

Đánh Giá Sự Biến Đổi Tế Bào Nội Mô Sau Phẫu Thuật Phaco Với Đường Rạch 2,2 Mm Giữa Bệnh Nhân Có Và Không Có Đái Tháo Đường Týp 2

“…Biến đổi tế bào nội mô sau phẫu thuật. Nghiên cứu của chúng tôi thực hiện khảo sát mật độ và hình thái tế bào nội mô cũng như chiều dày giác mạc bằng máy NIDEK CEM -530 (Nhật), máy tiến hành chụp hình tế bào nội mô ở vị trí trung tâm và cạnh trung tâm, phân tích hình chụp bằng phương pháp center-to-center với sai số 0,5 -5%, như vậy, thoả theo tiêu chuẩn khuyến cáo của các tác giả Binder (1976) [3] và Osama (2017) [8].…”