Corneal Cross-linking in Children

Hamada, Samer; Barua, Ankur; Caporossi, Aldo; Villano, Antonio; Caporossi, Orsola; Fasciani, Romina; Jarade, Elias

doi:10.1007/978-3-319-39775-7_8

Cited by 3 publications

(4 citation statements)

References 90 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this vulnerable demographic it may be prudent to stick with the traditional Dresdon protocol, which has been shown to have the maximum effectiveness, but various protocols aimed at reducing the treatment duration, shortening the recovery period and reducing discomfort are also being explored. 46 …”

Section: Main Textmentioning

confidence: 99%

See 1 more Smart Citation

Paediatric cornea crosslinking current strategies: A review

Prasher

Sharma²,

Sharma³

et al. 2023

Advances in Ophthalmology Practice and Research

View full text Add to dashboard Cite

Section: Main Textmentioning

confidence: 99%

“…These include chemical enhancers, epithelial disruption devices, intrastromal channels, microneedling, iontophoresis, ultrasound, and vacuum. 39 , 46 In pediatrics, where more patients are prone to infection, haze, surgical pain, and transient visual impairment, epithelium-on-crosslinking appears even more tempting.…”

Section: Main Textmentioning

confidence: 99%

Paediatric cornea crosslinking current strategies: A review

Prasher

Sharma²,

Sharma³

et al. 2023

Advances in Ophthalmology Practice and Research

View full text Add to dashboard Cite

“…The youngest patients with KCN were 4 years of age: a girl with persistent eye rubbing and another one with Down syndrome (who in fact, underwent CXL). 90 – 92 Furthermore, modern ophthalmologists are more aware of KCN, and with the available diagnostic tools, it can be detected in very young children (as young as 4 years old, as mentioned), so the cornea specialist faces the dilemma of treating a child without evidence of progression or waiting until progression occurs. Now, as mentioned before, according to a panel of experts and other several authors, if there are risk factors that make progression very likely, CXL is indicated without an age limit.…”

Section: Patient Selectionmentioning

confidence: 99%

“… 89 , 98 Therefore, the possibility of requiring an additional CXL should be considered when progression is found after the first procedure. 99 Some parameters have been suggested by Hamada et al 90 to determine the indication of a new CXL treatment: increase in the flattest K (K1), steepest K (K2), or K max >1 D, a change in the difference map between two consecutive topographies by 1 D, a deterioration of CDVA or any consistent change in the refractive astigmatism. 87 …”

Section: Patient Selectionmentioning

confidence: 99%

Patient selection for corneal collagen cross-linking: an updated review

Galvis

Tello

Ortiz

et al. 2017

OPTH

View full text Add to dashboard Cite

Corneal cross-linking (CXL) is an option that in the last decade has demonstrated its efficacy and safety in halting the progression of keratoconus (KCN) and other corneal ectasias. Its indication has been extended beyond the classic definition that required evidence of KCN progression, especially in the presence of some risk factors for a possible progression (particularly the younger age). However, the results can be still somewhat variable today. There are several protocols, each with its own advantages and disadvantages. Some predictors of CXL outcome have been identified. We will review the current knowledge on patient selection for CXL, its indications, and options in special cases (such as thin corneas).

show abstract

Keratoconus: The Masquerade.

2019

cjoec

View full text Add to dashboard Cite

Abstract We describe the case of an 11-year-old girl with a background of anisometropia and corneal scarring who had a misleading appearance of keratoconus. The patient initially presented at age 6 with a unilateral reduction of visual acuity (VA) in her left eye (6/15). There was also evidence of left corneal scarring which appeared chronic; possibly secondary to previous herpes simplex keratitis (HSK). She was treated with glasses and though her vision initially stabilized (VA 6/6 in both eyes), she was lost to follow-up due to multiple missed appointments. Her vision remained stable for 5 years before she presented with another reduction of VA in her left eye (6/48). The patient was investigated using Pentacam which showed ectatic changes suggestive of keratoconus. There was also progression of the corneal scar in her left eye. With an impression of active stromal herpetic keratitis, the patient was commenced on 200 mg Acyclovir TDS and Dexamethasone minims TDS. 2 months later, her VA improved to 6/7.5 in the left eye. Pentacam was then repeated and the astigmatism, as well as anterior steepening values had reduced. Considering this, clearly HSK had led to a misleading appearance of keratoconus upon initial imaging. This case highlights the potential false positive diagnosis of keratoconus that can occur in younger patients with HSK. Although pentacam results showed advanced ectasia, one should remain mindful of differential diagnoses; particularly seeking out any signs of herpetic eye disease and keeping a low threshold for appropriate treatment.

show abstract

Corneal Cross-linking in Children

Cited by 3 publications

References 90 publications

Paediatric cornea crosslinking current strategies: A review

Paediatric cornea crosslinking current strategies: A review

Patient selection for corneal collagen cross-linking: an updated review

Keratoconus: The Masquerade.

Contact Info

Product

Resources

About