Corneal Confocal Microscopy – A Novel, Noninvasive Method to Assess Diabetic Peripheral Neuropathy

Inceu, Georgeta; Demea, Horea; Vereşiu, Ioan Andrei

doi:10.2478/rjdnmd-2014-0039

Cited by 2 publications

(2 citation statements)

References 22 publications

(17 reference statements)

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“…For clinical research, the diagnosis of DPN requires at least two tests in addition to the clinical history and examination: these normally comprise quantitative sensory testing (QST) and electrophysiology (EP). Lately, promising new techniques have arised, such as intra-epidermal nerve fiber density, nerve biopsy and corneal confocal microscopy [ 10 ].…”

Section: General Aspects About Diabetic Neuropathymentioning

confidence: 99%

“…Among quantitative sensory testing, measurement of current perception threshold (CPT) using the Neurometer® (Neurotron Inc., Baltimore, Maryland, USA) has been proved to be a reliable method to asses DPN [ 10 , 11 ]. The technology has been available since 1989, and its employment has progressively increased in the past years, with applicability in both clinical use and human research.…”

Section: Current Perception Threshold Using the Neurometer® - Descripmentioning

confidence: 99%

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Measurement of Current Perception Thresholds Using the Neurometer® – Applicability in Diabetic Neuropathy

Inceu

Vereşiu

2015

Medicine and Pharmacy Reports

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The incidence of diabetes mellitus is continuously growing worldwide, while the specific chronic complications that it induces have a negative impact on life expectancy andquality, entailing extremely high costs of healthcare services. Diabetic peripheral neuropathy is one of the most common chronic complications of diabetes, affecting almost half of diabetic people during life.This review aims at summarizing the evidence on the advantages and the usefulness of current perception threshold measurement for peripheral diabetic neuropathy assessment. Among the different methods used for the screening and diagnosis of diabetic neuropathy, measurement of current perception threshold using the Neurometer® has the ability to assess three sub-types of nerve fiber by producing transcutaneous electrical stimuli at frequencies of 2000, 250 and 5 Hz.Current evidence shows that this method provides a useful, noninvasive evaluation technique of patients with peripheral nervous system disorders, being able to detect neuropathy in the earliest and asymptomatic stages.

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Section: General Aspects About Diabetic Neuropathymentioning

confidence: 99%

Section: Current Perception Threshold Using the Neurometer® - Descripmentioning

confidence: 99%

Measurement of Current Perception Thresholds Using the Neurometer® – Applicability in Diabetic Neuropathy

Inceu

Vereşiu

2015

Medicine and Pharmacy Reports

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Assessment of Nerve Fibers Dysfunction Through Current Perception Threshold Measurement in Diabetic Peripheral Neuropathy

Inceu

Román

Vereşiu

2017

International Conference on Advancements of Medicine and Health Care Through Technology; 12th - 15th October 2016, Cluj-Napoca,

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Corneal Confocal Microscopy – A Novel, Noninvasive Method to Assess Diabetic Peripheral Neuropathy

Abstract: Background and aims. This article aims to compare corneal confocal microscopy (CCM) with acknowledged tests of diabetic peripheral neuropathy (DPN

Cited by 2 publications

References 22 publications

Measurement of Current Perception Thresholds Using the Neurometer® – Applicability in Diabetic Neuropathy

Measurement of Current Perception Thresholds Using the Neurometer® – Applicability in Diabetic Neuropathy

Assessment of Nerve Fibers Dysfunction Through Current Perception Threshold Measurement in Diabetic Peripheral Neuropathy

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