Corneal Biomechanics, Refractive Error, and Axial Length in Chinese Primary School Children

Abstract

CH measurement is practical in young children because this is when myopia undergoes its most rapid progression. Prospective follow-up of this cohort at high risk for myopia is under way to determine whether low CH is predictive, or a consequence, of long AL.

Corneal resistance factor and corneal hysteresis in a 6- to 18-year-old population

“…Table 4 is a summary of results in studies of other populations. [9][10][11][12][14][15][16][17][18][19][20]25 As seen, the mean corneal biomechanical properties in some East Asian countries were lower than in our study.…”

“…From previous studies, 23,24 we know that girls have a smaller AL than boys. Also, findings in some studies 9,25 suggest an inverse association between biomechanical properties and AL. Thus, the higher CRF and CH values in girls may be due to their smaller AL.…”

“…12 The only studies on average CH and CRF values in children are from China and Singapore. 9,10 These geographic areas are known to have a high prevalence of myopia; thus, the results in these studies are not applicable to all areas of the world. Due to the ethnic, geographic, and genetic changes in Ocular Response Analyzer measurements, knowledge of the average and normal ranges of CH and CRF values in children and adolescents in each geographic area and ethnicity can be beneficial.…”

“…7 Some studies [8][9][10] have evaluated the normal ranges of these indices in different samples. In most studies, the mean CH and the CRF in normal eyes range between 10 mm Hg and 11 mm Hg, [8][9][10] and the reported range in normal populations is between 8 mm Hg and 16 mm Hg. 11 Indices found to be correlated with CH and the CRF include the central corneal thickness (CCT) and intraocular pressure (IOP).…”

Axial Length and Associated Factors in Children: The Shandong Children Eye Study

“…Previous population-based studies mainly focused on the refractive error (RE), its distribution and its associated factors in adults, with only few investigations focusing on children [1,2,3,4,5]. In particular for children, population-based studies only rarely assessed AL, although AL as compared to RE may be more predictive and may be the primary factor for the eventual development of axial elongation-associated myopic stretching and changes in the macula and optic nerve head [6].…”