Corneal Biomechanical Parameters during Pregnancy

Abstract

Hormonal changes during pregnancy may not affect corneal biomechanics. This may be due to the balanced effect of the various hormones on the cornea during pregnancy.

Topographic, tomographic and biomechanical corneal changes during pregnancy in patients with keratoconus: a cohort study

“…This effect does not have any influences on normal corneas; however, it affects weakened corneas such as keratoconic or postrefractive laser surgery corneas (Spoerl et al +3.20* À0.80 +4.00* À11.29%* À2.75* CCT = central corneal thickness; D = dioptre; K = keratometry; Max = maximum; Min = minimum; MRSE = manifest refraction spherical equivalent. In contrast, Goldich et al (2014) and Sen et al (2014) did not report CH and CRF values to be significantly different in pregnant and non-pregnant normal women. The results of criterion 5 (corneal apex power ≥ 1 D increase) were similar to the criterion 3 (mean K ≥ 0.75 D increase) and, therefore, were not included in the table.…”

“…In the present study, CH and CRF values were significantly decreased during the pregnancy. In contrast, Goldich et al (2014) and Sen et al (2014) did not report CH and CRF values to be significantly different in pregnant and non-pregnant normal women. However, Goldich et al (2011) found a decrease in CH and CRF values during menstrual and ovulation cycle, which may be associated with higher levels of oestrogen at the time of ovulation.…”

Ophthalmic Complications and Ocular Changes in Pregnancy- A Review

“…Glaucoma: Glaucoma is another preexisting disease modified by pregnancy. As mentioned earlier, intraocular pressure is decreased during pregnancy [11][12][13][14][15]. Intraocular pressure decreases during the second trimester and continues to decrease with the advancing pregnancy [13].…”

“…Intraocular pressure can also be affected. It can be significantly decreased during pregnancy [12][13][14][15].…”

Impact of oral contraceptive pills on central corneal thickness in young women

“…Because of the balanced effect of the various hormones on the cornea during pregnancy, corneal biomechanics may not be changed. [14] In addition, hormone replacement therapy and lifetime estrogen and progesterone exposure do not seem to affect IOP or the risk for increased IOP. [15] In another study, protective role of female hormones was mentioned in women with primary open angle glaucoma (POAG).…”