Corneal Arcus and Its Associations with Ocular and General Parameters: The Central India Eye and Medical Study

Abstract

In this adult rural Central Indian population with low mean BMI, the prevalence of corneal arcus was 10.7% ± 1.0%. The only systemic parameter associated with corneal arcus was increasing age (P < 0.001). Corneal arcus was not associated with dyslipidemia, diabetes mellitus, arterial hypertension, alcohol consumption, or smoking. In this population with low BMI, corneal arcus was not a clinical biomarker for major metabolic disorders. The intereye associations between corneal arcus and low intraocular pressure, thin central cornea, and hyperopia may be of importance in the ophthalmic examination.

A Population-based Study of Corneal Arcus and its Risk Factors in Iran

“…As demonstrated, prevalence was significantly correlated with age in men and women, and in agreement with our results, several studies have shown lower prevalence rates in women. 1,2,8,12,[15][16][17] According to our findings, the prevalence of corneal arcus increased by 10% per 5 years of age. A correlation with age has been shown in many studies 1,2,12,16 and the correlation is so evident that the condition is also known as arcus senilis and arcus senilis cornea, although it may rarely be seen in the young as well.…”

“…Other studies have inconclusive results on this association. Ang and colleagues, 17 Wu and colleagues 2 and Fernandez and colleagues 15 have shown that corneal arcus and smoking are related, while studies by Vurgese and co-workers, 12 Chua and co-workers 1 and Hughes and co-workers 19 did not show such an association.…”

“…Chen and colleagues 22 reported a similar relation, while a greater number of studies did not show any relation with systolic blood pressure. 2,12,17 Since the relation between corneal arcus and blood pressure remained in the multivariable adjusted model after adjusting for age and sex, the association is not due to age. According to Wu and co-authors 2 , corneal arcus is related to chronic renal disease, which may partly explain the association with blood pressure.…”

Ophthalmologic Findings in H Syndrome: A Unique Diagnostic Clue

“…12 Although the presence of corneal arcus in a 50-year-old patient may not be considered as unique, previously reported H syndrome patients with corneal arcus were mostly children and young adults ( Figure 3C, D). The presence of corneal arcus in children and young adults is very rare and is mainly seen in inherited disorders of lipid metabolism due to deposition of lipid aggregates in the collagenous connective tissue of the cornea.…”

Schlemm's Canal Expands After Trabeculectomy in Patients With Primary Angle–Closure Glaucoma

“…3 One possible reason is that the patients with PACG were significantly older than the two other groups, who tend to develop arcus senilis and pterygium. 7,8 Previous studies have demonstrated the advantages of adaptive compensation, including removal of noise overamplification in the deep layers of the tissue and improved visibility of the posterior tissue boundary (such as SC in our study). 6,9 However, this technique is not available for all subjects.…”