Cork workers? occupational asthma: lack of association with allergic sensitisation to fungi of the work environment

Delgado, Luís; Murta, R.; Vanzeller, Manuela; Marques, José António

doi:10.1007/s00420-003-0494-x

Cited by 8 publications

(5 citation statements)

References 27 publications

(33 reference statements)

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“…Atopy is reported to increase the risk of OA in workers exposed to enzymes, 38 62 63 isocyanates, 47 64 laboratory and other animals, 50-52 64 65-74 bakery allergens, 44 75-79 and some reactive dyes. 80 Other studies show no association between atopy and OA due to exposure to cork, 81 isocyanates, 48 82 83 enzymes, 35 glutaraldehyde, 84 salmon, 85 crab, 86 hexahydrophthalic anhydride, 87 platinum salts, 61 88 and plicatic acid. 89 Atopy is associated with increased risk of sensitisation in workers exposed to enzymes, 36 86 prawn, 55 and acid anhydrides.…”

Section: ++mentioning

confidence: 99%

Evidence based guidelines for the prevention, identification, and management of occupational asthma

Nicholson¹

2005

Occup Environ Med

271

199

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Background:Occupational asthma is the most frequently reported work related respiratory disease in many countries. This work was commissioned by the British Occupational Health Research Foundation to assist the Health and Safety Executive in achieving its target of reducing the incidence of occupational asthma in Great Britain by 30% by 2010.Aim:The guidelines aim to improve the prevention, identification, and management of occupational asthma by providing evidence based recommendations on which future practice can be based.Methods:The literature was searched systematically using Medline and Embase for articles published in all languages up to the end of June 2004. Evidence based statements and recommendations were graded according to the Royal College of General Practitioner’s star system and the revised Scottish Intercollegiate Guidelines Network grading system.Results:A total of 474 original studies were selected for appraisal from over 2500 abstracts. The systematic review produced 52 graded evidence statements and 22 recommendations based on 223 studies.Discussion:Evidence based guidelines have become benchmarks for practice in healthcare and the process used to prepare them is well established. This evidence review and its recommendations focus on interventions and outcomes to provide a robust approach to the prevention, identification, and management of occupational asthma, based on and using the best available medical evidence. The most important action to prevent cases of occupational asthma is to reduce exposure at source. Thereafter surveillance should be performed for the early identification of symptoms, including occupational rhinitis, with additional functional and immunological tests where appropriate. Effective management of workers suspected to have occupational asthma involves the identification and investigation of symptoms suggestive of asthma immediately they occur. Those workers who are confirmed to have occupational asthma should be advised to avoid further exposure completely and early in the course of their disease to offer the best chance of recovery.

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Section: ++mentioning

confidence: 99%

Evidence based guidelines for the prevention, identification, and management of occupational asthma

Nicholson¹

2005

Occup Environ Med

271

199

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“…Segundo Winck et al (2004), a exposição dos corticeiros a fungos no seu local de trabalho pode induzir o desenvolvimento de suberose. Ambos os fungos identificados neste estudo foram também confirmados em quase todas as amostras do estudo de Prat, Ruiz-Rueda, et al, (2009).…”

Section: Discussionunclassified

International Symposium on Occupational Safety and Hygiene: Proceedings Book of the SHO2018

2018

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A Sociedade Portuguesa de Segurança e Higiene Ocupacionais realiza, em 26 e 27 de Março de 2018, a 14ª edição do Colóquio Internacional de Segurança e Higiene Ocupacionais - SHO 2018. Tal como nos doze últimos anos, o evento tem lugar no Auditório Nobre da Escola de Engenharia da Universidade do Minho, em Guimarães. A edição de 2018 abrange as temáticas da Ergonomia e do Ambiente Físico, dos Riscos Químicos e Biológicos, da Segurança contra Incêndio e da Gestão da Prevenção, que são objeto de sessões plenárias, decorrendo ainda várias sessões paralelas de comunicações livres nas 26 áreas temáticas previstas para o evento, bem como várias sessões com apresentação de posters.

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“…T. viride did not produce positive skin prick reactions (Khan et al, 2009), and T. longibrachiatum did not cause allergic reactions in asthma patients (Winck et al, 2004). Results were inconclusive in the study concerning allergic effects of grass pollen infected with Cocksfoot streak virus (Pallett et al, 2009).…”

Section: Methods Used To Explore Adverse Effects Of Microbial Ppps Onmentioning

confidence: 99%

“…Barbieri et al, 2005;Das and Gupta-Bhattacharya, 2009), agar-gel precipitation tests (Góra et al, 2004), assays for inhibition of leukocyte migration in the presence of specific antigens (Góra et al, 2004), and in IgE-and IgG4-reactivity analyses (e.g. Westwood et al, 2006;Winck et al, 2004). In one allergy-related study, sensitized mice received an intranasal dose of B. licheniformis, and lung histology as well as the detection of cells and cytokines in bronchoalveolar lavage fluid were used to detect the effects of this treatment (Vogel et al, 2008).…”

Section: Methods Used To Explore Adverse Effects Of Microbial Ppps Onmentioning

confidence: 99%

Literature search and data collection on RA for human health for microorganisms used as plant protection products

Hackl

Pacher‐Zavisin

Sedman

et al. 2015

EFSA Supporting Publications

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A knowledge base of scientific and regulatory data relevant in the context of risk assessment of microbial plant protection products (PPPs) for human health was established, taking into consideration conditions 1 to 4 in Regulation (EU) 546/2011 that must be met before authorisation can be granted. We screened scientific publications and documents from governmental and institutional sources and extracted relevant information into a database, performed comparative genome analyses to explore possibilities and limitations of applying read-across among PPP strains, and discussed the collective findings among a group of experts in relevant fields. Besides information on factors relevant for the evaluation of microbial PPP strains regarding pathogenicity, infectivity, and toxicity, information was collected on methods used to analyse the PPP species' ability to persist and grow in test animals, for detecting microbial DNA transfer, for testing microbial compounds for potential toxicity, and for detecting toxin production from PPP strains. Questions arising from the reviewed scientific and grey literature were how to address the specific biological properties of PPP strains and how to take into consideration realistic exposure scenarios and a natural background of environmental microorganisms in the risk assessment. Results from the present work imply that pathogenicity traits have to be considered as strain specific and that, hence, read-across comparison cannot be used. From a scientific point of view, it was highly recommended to provide whole genome sequencing data of PPP strains to allow their unambiguous identification, while other technological developments such as the use of metabolomics data were seen as an option for future implementation. It is envisaged to further develop the key topics of the present work at a joint stakeholder workshop as the next step towards the preparation of a guidance document by the PPR panel on how to conduct the regulatory risk assessment for microbial pesticides. © Efsa 2015Key words: microorganism, pesticide, risk assessment, human health, toxicity, read-across, DNA sequencing Disclaimer: The present document has been produced and adopted by the bodies identified above as authors. This task has been carried out exclusively by the authors in the context of a contract between the European Food Safety Authority and the authors, awarded following a tender procedure. The present document is published complying with the transparency principle to which the Authority is subject. It may not be considered as an output adopted by the Authority. The European Food Safety Authority reserves its rights, view and position as regards the issues addressed and the conclusions reached in the present document, without prejudice to the rights of the authors.Suggested citation: Evelyn Hackl1), Margit Pacher-Zavisin2), Laura Sedman1), Stefan Arthaber1), Ulla Bernkopf1), Günter Brader1), Markus Gorfer1), Birgit Mitter1), Aspasia Mitropoulou1), Monika Schmoll1), Willem van Hoesel1), Elisabeth Wis...

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Cork workers? occupational asthma: lack of association with allergic sensitisation to fungi of the work environment

Cited by 8 publications

References 27 publications

Evidence based guidelines for the prevention, identification, and management of occupational asthma

Evidence based guidelines for the prevention, identification, and management of occupational asthma

International Symposium on Occupational Safety and Hygiene: Proceedings Book of the SHO2018

Literature search and data collection on RA for human health for microorganisms used as plant protection products

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