Core genome multilocus sequence typing of Clostridioides difficile to investigate transmission in the hospital setting
Paraskevas Filippidis,
Laurence Senn,
Fabrice Poncet
et al.
Abstract:Purpose
Traditional epidemiological investigations of healthcare-associated Clostridioides difficile infection (HA-CDI) are often insufficient. This study aimed to evaluate a procedure that includes secondary isolation and genomic typing of single toxigenic colonies using core genome multilocus sequence typing (cgMLST) for the investigation of C. difficile transmission.
Methods
We analyzed retrospectively all toxigenic C. difficile-positive stool samples s… Show more
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