Cord blood collection after cesarean section improves banking efficiency

Gutman, Jonathan A.; Miller, Sam S.; Kuenne, Sarah; Oppenheim, Jane; Quinones, Ralph; Freed, Brian M.; Stark, Craig; Zarlengo, Gerald

doi:10.1111/j.1537-2995.2011.03249.x

Cited by 6 publications

(4 citation statements)

References 9 publications

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“…To address this problem, we raised the TNC pre-and postprocessing acceptance levels in January 2014. Although this resulted in a higher discard rate as recognized above, but a higher TNC count of around 15x10 8 in accepted units, which is in better agreement with the cell content of shipped units reported by most banks (Gutman et al 2011;Lee et al 2013;Querol et al 2010).…”

Section: Discussionsupporting

confidence: 85%

High quality cord blood banking is feasible with delayed clamping practices. The eight-year experience and current status of the national Swedish Cord Blood Bank

et al. 2016

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The National Swedish Cord Blood Bank (NS-CBB) is altruistic and publicly funded. Herein we describe the status of the bank and the impact of delayed versus early clamping on cell number and volume. Cord Blood Units (CBUs) were collected at two University Hospitals in Sweden. Collected volume and nucleated cell content (TNC) were investigated in 146 consecutive Cord Blood (CB) collections sampled during the first quarter of 2012 and in 162 consecutive CB collections done in the first quarter of 2013, before and after clamping practices were changed from immediate to late (60 s) clamping. NS-CBB now holds close to 5000 units whereof 30 % are from non-Caucasian or mixed origins. Delayed clamping had no major effect on collection efficiency. The volume collected was slightly reduced (mean difference, 8.1 ml; 95 % CI, 1.3-15.0 ml; p = 0.02), while cell recovery was not (p = 0.1). The proportion of CBUs that met initial total TNC banking criteria was 60 % using a TNC threshold of 12.5 × 10(8), and 47 % using a threshold of 15 × 10(8) for the early clamping group and 52 and 37 % in the late clamping group. Following implementation of delayed clamping practices at NS-CBB; close to 40 % of the collections in the late clamping group still met the high TNC banking threshold and were eligible for banking, implicating that that cord blood banking is feasible with delayed clamping practices.

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Section: Discussionsupporting

confidence: 85%

High quality cord blood banking is feasible with delayed clamping practices. The eight-year experience and current status of the national Swedish Cord Blood Bank

et al. 2016

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“…Additional findings of our study include a higher proportion of CBUs with TNC count of more than 1600 × 10 6 obtained from vaginal deliveries than from Cesarean sections, different from the previously published results, and an approximately equal number of clinical CBUs from male and female infant donors. These findings may reflect different obstetric practices at different hospitals, CB collection techniques, and/or a weaker correlation between CBU volume and TNC at the high TNC ranges (volume and TNC Pearson coefficient r = 0.3 in our cohort, consistent with our data since this TNC threshold was introduced).…”

Section: Discussioncontrasting

confidence: 99%

Impact of delayed umbilical cord clamping on public cord blood donations: can we help future patients and benefit infant donors?

et al. 2018

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“…Our results have some points of coincidence with those of other authors showing increased volume and cell content for vaginal deliveries 2,3 . In contrast, Gutman and coworkers 4 showed higher volume and TNC content in UCB units from cesarean deliveries. However, our study shows similar low positive microbiologic rate for UCB from cesarean sections than this study (<1%).…”

Section: Obstetric Data In Cesarean and Vaginal Deliveries *supporting

confidence: 92%

“…UCB can be collected from vaginal and cesarean deliveries. Influence of mode of delivery on cord blood quality remains controversial 2‐4 . Our group has previously failed to show any influence of mode of delivery on UCB hematopoietic cell content 5 .…”

Section: Obstetric Data In Cesarean and Vaginal Deliveries *mentioning

confidence: 90%