Cord blood banking

Brand, Anneke; Rebulla, Paolo; Engelfriet, C. P.; Reesink, H. W.; Béguin, Yves; Baudoux, Étienne; Kögler, Gesine; Ebrahimi, Maryam; Grazzini, Giuliano; Costa, Alessandro Nanni; Bosi, Alberto; Sacchi, Nicoletta; Lombardini, Letizia; Pupella, Simonetta; Lecchi, Lucilla; Garcidueñas, Eva Delia Calderón; Beckhoven, J. M. van; Wit, H. J. C. de; Fibbe, W. E.; Жибурт, Е Б; Bart, Thomas; Beksaç, Meral; Navarrete, Cristina; Regan, Fiona

doi:10.1111/j.1423-0410.2008.01106.x

Cited by 31 publications

(28 citation statements)

References 65 publications

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“…The efficacy of cord blood hemopoietic stem cells for the treatment of a number of severe conditions is convincingly supported by several studies and general consensus [1][2][3]. Nevertheless, the cord blood worldwide inventory is still sub-optimal to fully satisfy the needs for unrelated transplantation, in particular for small ethnic groups [4].…”

Section: Introductionmentioning

confidence: 96%

An analysis of decision making in cord blood donation through a participatory approach

Salvaterra

Casati

Bottardi

et al. 2010

Transfusion and Apheresis Science

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a b s t r a c tWe analysed knowledge, comprehension, opinions, attitudes and choices related to cord blood donation in seven heterogeneous focus groups including pregnant women, future parents, cord blood donors, midwives and obstetricians/gynaecologists. Comparative evaluations focused on attitudes before versus after delivery and preferences of public versus private banking. The study outlined large support to altruistic cord blood donation and need for better health professionals education in this field. Collected information was presented in a public conference and used to develop an informative brochure which was tested for readability and clearliness in four workshops and finally distributed to 26 regional delivery suites.

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Section: Introductionmentioning

confidence: 96%

An analysis of decision making in cord blood donation through a participatory approach

Salvaterra

Casati

Bottardi

et al. 2010

Transfusion and Apheresis Science

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“…In the last 20 years several cord blood banks have been created worldwide in order to collect and store related and unrelated CB units for the treatment of hematological disorders [2][3][4]. Today, there are more than 100 active CB banks with an inventory of more than 400,000 CB units that have generated more than 10,000 CB transplants all around the world [5].…”

Section: Introductionmentioning

confidence: 99%

Platelet gel from cord blood: A novel tool for tissue engineering

2010

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Recent findings show that growth factors (GF) play a relevant role in regenerative medicine. Platelets (PLT) may be used as “drug-stores” of GF that can be released upon activation by PLT granules. In this context, PLT gel (PG) from peripheral blood is currently used to improve tissue healing in orthopedic, oral maxillofacial and dermatologic surgery. Recent findings on multiple biological properties of human umbilical cord blood (CB) and its high level of viral safety prompted us to investigate the characteristics of its PLTs and the possibility to produce PLT gel from cord blood. Our study shows that CB PG releases high levels of vascular endothelial growth factor (VEGF) and platelet-derived growth factor-BB (PDGF-BB), substantial amounts of fibroblast growth factor (FGF), hepatocyte growth factor (HGF) and transforming growth factor-beta 1 (TGFbeta1), and minimal amounts of PDGF-AB. These findings suggest that CB PG can be a preferable tool for tissue engineering applications where high levels of VEGF and PDGF may be desirable.

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“…It underpins not only official opinions of bioethics and medicalprofessional bodies (American Academy of Pediatrics, 1999; European Group on Ethics in Science and New Technologies, 2004; Royal College of Obstetricians and Gynaecologists, 2006; ACOG Committee on Obstetric Practice, 2008), but also biomedicine's discussions on UCB banking (for example Brand et al, 2008;Sullivan, 2008;Ballen, 2010) and bioethics and medical ethics literature (for example Sugarman et al, 1995;Annas, 1999;Ecker and Green, 2005;Samuel et al, 2008). In the biomedical and bioethical discourses, this narrative is mobilized against a private economy that might undermine public banking and future redistributive practices in health and care provision.…”

Section: Introductionmentioning

confidence: 99%

The hybrid bioeconomy of umbilical cord blood banking: Re-examining the narrative of opposition between public and private services

Hauskeller

Beltrame

2016

BioSocieties

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Umbilical cord blood (UCB) is an important source for stem cells used in clinical treatments. For this purpose, UCB has to be collected at birth and stored in biobanks. The discourse about UCB biobanking practices commonly holds that it occurs in two opposite economies, the public sector and a competing private one. They correspond with moral economies of gift-giving in a redistributive economy versus private ownership of cord blood in a market economy. Our analysis of UCB banking in Europe shows that this opposition narrative is both empirically and analytically unsatisfactory. Using the analytic concepts of entanglement (Callon) and biomedical platforms (Keating and Cambrosio), we demonstrate how the network of actors, objects, interests and practices in biobanking creates different kinds of value and shared issues across public and private services. Our case study illustrates how the interrelation between technical, ethical, economic and logistical considerations plays out and generates a field of practices where redistributive and market economies coexist, are co-dependent and hybridize each other. The narrative of opposition therefore can inform STS studies regarding the normative values written into the public facing side of biobanking, but bioeconomic analyses benefit from building on concepts that enable the examination of the complex interrelations between the wider network of heterogeneous elements on which UCB banking relies.

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Cord blood banking

Cited by 31 publications

References 65 publications

An analysis of decision making in cord blood donation through a participatory approach

An analysis of decision making in cord blood donation through a participatory approach

Platelet gel from cord blood: A novel tool for tissue engineering

The hybrid bioeconomy of umbilical cord blood banking: Re-examining the narrative of opposition between public and private services

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