Copro-eosinophil cationic protein (ECP) in food allergy

Kosa, Lajos; Kereki, E; Börzsönyi, L

doi:10.1111/j.1398-9995.1996.tb02147.x

Cited by 16 publications

(1 citation statement)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In agreement with the previous observations, a marked increase in ECP was also seen in faeces from patients with Crohn's disease or ulcerative colitis [ 131, 132]. Some studies indicate that ECP could be a disease activity marker of gut inflammation [ 131–133]. ECP was also increased in faeces of children with atopic eczema after cow's milk challenge and only in those who had positive clinical reaction [ 134].…”

Section: Ecp Measurements In Various Body Fluidssupporting

confidence: 87%

Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease

Venge¹,

Byström²,

Carlson³

et al. 1999

Clin Experimental Allergy

261

219

View full text Add to dashboard Cite

Section: Ecp Measurements In Various Body Fluidssupporting

confidence: 87%

Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease

Venge¹,

Byström²,

Carlson³

et al. 1999

Clin Experimental Allergy

261

219

View full text Add to dashboard Cite

Higher Serum Eosinophil Cationic Protein Levels in Children with Cow's Milk Allergy

Hidvégi,

Cserháti,

Kereki

et al. 2001

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

BackgroundIn the pathogenesis of cow's milk allergy, abnormal immunologically mediated reactions play a basic role. Eosinophil activation also participates in the development of several allergies. The purpose of this study was to characterize the degree of this activation by measuring the serum level of eosinophil cationic protein (sECP) and establishing whether it is a useful parameter in monitoring oral cow's milk allergy.MethodsThe sECP level of 35 patients with previously confirmed cow's milk allergy (mean age, 16 months) was evaluated using a fluoroimmunoassay before the cow's milk rechallenge test and at 2 hours and 24 hours after cow's milk challenge.ResultsOf the 35 children with previously confirmed cow's milk allergy, 10 had positive clinical reactions after the milk rechallenge test, whereas 25 children had no reaction. The median sECP level of all the patients before the challenge test was significantly higher (12.4 μg/L) than that of the control group (4.3 μg/L) (P < 0.05). Two hours after the challenge, the median sECP of all patients (9.4 μg/L) was lower than the starting values. The median sECP levels were higher in children with positive challenge test results at all time points. However, this difference was not statistically significant.ConclusionsThe normalization of sECP level may indicate the cessation of the cow's milk allergy. Therefore, the measurement of sECP may be helpful in determining the optimal time in which to repeat the challenge test, when the result will more likely be negative. The significant decrease of the sECP level 2 hours after the beginning of milk challenge test may be explained by the fact that this protein is excreted into the intestinal lumen.

show abstract

Nahrungsmittelallergie

Bischoff¹

Therapie Gastroenterologischer Krankheiten

View full text Add to dashboard Cite

Copro-eosinophil cationic protein (ECP) in food allergy

Cited by 16 publications

References 4 publications

Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease

Eosinophil cationic protein (ECP): molecular and biological properties and the use of ECP as a marker of eosinophil activation in disease

Higher Serum Eosinophil Cationic Protein Levels in Children with Cow's Milk Allergy

Nahrungsmittelallergie

Contact Info

Product

Resources

About