Copper sulfide-functionalized molybdenum disulfide nanohybrids as nanoenzyme mimics for electrochemical immunoassay of myoglobin in cardiovascular disease

Zhang, Bo; Zhang, Yi; Liang, Wenbin; Yu, Xin; H, Tan; Wang, Guoqiang; Li, Aimin; Jin, Jun; Huang, Lan

doi:10.1039/c6ra26372k

Cited by 21 publications

(13 citation statements)

References 44 publications

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“…Electrochemical immunosensors (EIs) have received considerable attention due to their high sensitivity, low cost, simple instrumentation and operation, and inherent miniaturization [ 214 , 215 , 216 ]. They show great potential in the next-generation of point-of-care (POC) diagnostics for early detection and monitoring of diseases.…”

Section: Application Of 2d Mos 2 -Based Nanocompos...mentioning

confidence: 99%

Functionalization of 2D MoS2 Nanosheets with Various Metal and Metal Oxide Nanostructures: Their Properties and Application in Electrochemical Sensors

2022

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Two-dimensional transition metal dichalcogenides (2D TMDs) have gained considerable attention due to their distinctive properties and broad range of possible applications. One of the most widely studied transition metal dichalcogenides is molybdenum disulfide (MoS2). The 2D MoS2 nanosheets have unique and complementary properties to those of graphene, rendering them ideal electrode materials that could potentially lead to significant benefits in many electrochemical applications. These properties include tunable bandgaps, large surface areas, relatively high electron mobilities, and good optical and catalytic characteristics. Although the use of 2D MoS2 nanosheets offers several advantages and excellent properties, surface functionalization of 2D MoS2 is a potential route for further enhancing their properties and adding extra functionalities to the surface of the fabricated sensor. The functionalization of the material with various metal and metal oxide nanostructures has a significant impact on its overall electrochemical performance, improving various sensing parameters, such as selectivity, sensitivity, and stability. In this review, different methods of preparing 2D-layered MoS2 nanomaterials, followed by different surface functionalization methods of these nanomaterials, are explored and discussed. Finally, the structure–properties relationship and electrochemical sensor applications over the last ten years are discussed. Emphasis is placed on the performance of 2D MoS2 with respect to the performance of electrochemical sensors, thereby giving new insights into this unique material and providing a foundation for researchers of different disciplines who are interested in advancing the development of MoS2-based sensors.

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Section: Application Of 2d Mos 2 -Based Nanocompos...mentioning

confidence: 99%

Functionalization of 2D MoS2 Nanosheets with Various Metal and Metal Oxide Nanostructures: Their Properties and Application in Electrochemical Sensors

2022

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“…Table 2 shows the table of cardiac function status in mice, and according to the data in the table, LVEDD and LVESD were significantly abnormal and IVS, LVEF, and LVFS were reduced in the model and drug groups compared to the sham-operated group [ 24 ].…”

Section: Diagnostic Imaging Analysis and Nursing Care Of Patients Wit...mentioning

confidence: 99%

Diagnostic Imaging Analysis and Care of Patients with Endomyocardial Fibrosis Based on Wireless Network Smart Medical Application

Chen¹,

Wen

2022

Journal of Healthcare Engineering

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The heart is one of the most important organs of the human body, but in recent years heart disease has become one of the human health killers and this paper explores endomyocardial fibrosis, which is a common cardiomyopathy, commonly seen in infants and children, and refers to a diffuse elastic fibrous disease of the endocardium. The purpose of this paper is to explore the diagnostic imaging analysis and care of patients with endocardial heart machine fibrosis using wireless network intelligent medical technology, aiming to provide a new power basis for the treatment of the disease in related patients. This paper proposes a new endocardial segmentation algorithm that aims to process image information using image features, intervene in image noise reduction and smoothing, etc., and use image grayscale values to confirm cardiac cavity grayscale values as a basis for physicians to make certain judgments for the diagnosis of patients with endocardial machine fibrosis. The experimental results show that the atrial fibrillation group is distinctly higher compared to the sinus rhythm group, with values remaining between 25 and 39, which is a significant advantage compared to other methods.

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“…Functional organic–inorganic hybrid materials are currently under the spotlight of material research. These tailor‐made materials with remarkable chemical and physical properties find applications in capacitors, biomedicine, batteries, solar cells, fuel cells, biosensors, and as heterogeneous catalysts . To be specific, there are recent reports on photocatalyst materials used for wastewater disinfection and decontamination, water splitting and hydrogen production, and targeted cancer cells therapy .…”

Section: Introductionmentioning

confidence: 99%

“…CuS obtained from this method successfully decomposed 95% of higher concentrations of MB (1000 mg L −1 ) in visible light spectrum in just 20 min with the assistance of H 2 O 2 by Photo‐Fenton type reactions, these kind of reactions are well considered for advanced oxidation processes for waste containments in water. Whereas, two recent reports on functionalized CuS catalyst are also available to use it in medical field applications, such as CuS‐functionalized ZnO nanoflakes for photo electrochemical immunoassay and CuS‐functionalized nanohybrid of molybdenum disulfide used for immunoassay of myoglobin in cardiovascular disease via electrochemical approach . Fenton‐like reactions of CuS were also reported elsewhere …”

Section: Introductionmentioning

confidence: 99%

CuS‐functionalized cellulose based aerogel as biocatalyst for removal of organic dye

Saeed

Bano

Sun

et al. 2018

J of Applied Polymer Sci

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CuS‐functionalized cellulose based aerogel (CBA) with 3D macroporous structure was synthesized by in situ deposition of visible light responsive CuS photocatalyst. Hexagonal CuS was deposited onto the outer and inner walls of CBA matrix. CuS/CBA composite catalyst has hierarchical porous structure and abundance in functional groups supporting CuS on CBA surface that enhance photodecomposition of methylene blue (MB). The CuS/CBA composite was characterized by XRD, FTIR, SEM‐EDS, Atomic Absorption Analysis, and XPS analysis. Photodegradation rate of MB by CuS/CBA composite catalyst in visible light was 94.1%, whereas, 67.4% for pure CuS. Initial MB concentration effects, pH change, and variations in CuS/CBA dosage on overall reaction kinetics were also studied. CuS/CBA composite catalyst carried out Photo‐Fenton like reactions which decomposed 97% MB within 6 min, by producing hydroxyl radicals from chemical and photocatalytic reactions. CuS/CBA composite catalyst was recycled and reused. It retained over 80% MB degradation rate even after five consecutive cycles. CuS/CBA composite can be used as biocatalyst for removal of organic dyes. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47404.

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Copper sulfide-functionalized molybdenum disulfide nanohybrids as nanoenzyme mimics for electrochemical immunoassay of myoglobin in cardiovascular disease

Abstract: Myoglobin is one of the most commonly used cardiac biomarkers for the clinical diagnosis of acute myocardial infarction, which is the leading cause of mortality worldwide.

Cited by 21 publications

References 44 publications

Functionalization of 2D MoS2 Nanosheets with Various Metal and Metal Oxide Nanostructures: Their Properties and Application in Electrochemical Sensors

Functionalization of 2D MoS2 Nanosheets with Various Metal and Metal Oxide Nanostructures: Their Properties and Application in Electrochemical Sensors

Diagnostic Imaging Analysis and Care of Patients with Endomyocardial Fibrosis Based on Wireless Network Smart Medical Application

CuS‐functionalized cellulose based aerogel as biocatalyst for removal of organic dye

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