Copper-(s)-N-methylpyrrolidine-2-carboxylate catalyzed N-Arylation of N⁵h-1,2,5-thiadiazolidine 1,1-dioxides

Abstract

A copper-catalyzed N-arylation of N 5 H-1,2,5-thiadiazolidine 1,1-dioxides derivatives (cyclic sulfamides) is described. Reactions were carried out using Ullmann-Goldberg-type condensation with (S)-N-methyl-2-carboxylate as the ligand, and N-arylated products were obtained with moderate to good yields. The structures of the synthesized compounds were confirmed based on analytical and spectral data.