2021
DOI: 10.1016/j.matlet.2021.129787
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Copper oxide nanoparticles infused electrospun polycaprolactone/gelatin scaffold as an antibacterial wound dressing

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Cited by 42 publications
(20 citation statements)
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“…In publication [ 62 ], the antibacterial properties of the nanofibers based on polycaprolactone and gelatin containing 1 wt.% CuO NPs were studied. It was determined that the nanofibers have a strong antibacterial activity against the Gram-positive S. aureus (51 ± 1.2 mm), the multidrug resistant S. aureus (40 ± 1.7 mm) and the Gram-negative P. aeruginosa (31 ± 0.5 mm) and the E. coli (30.5 ± 0.3 mm) bacteria, which was explained by the authors through generation of the reactive oxygen intermediates that destroy bacterial cells by cell membrane oxidation.…”
Section: Resultsmentioning
confidence: 99%
“…In publication [ 62 ], the antibacterial properties of the nanofibers based on polycaprolactone and gelatin containing 1 wt.% CuO NPs were studied. It was determined that the nanofibers have a strong antibacterial activity against the Gram-positive S. aureus (51 ± 1.2 mm), the multidrug resistant S. aureus (40 ± 1.7 mm) and the Gram-negative P. aeruginosa (31 ± 0.5 mm) and the E. coli (30.5 ± 0.3 mm) bacteria, which was explained by the authors through generation of the reactive oxygen intermediates that destroy bacterial cells by cell membrane oxidation.…”
Section: Resultsmentioning
confidence: 99%
“…Moreover, the antibacterial performance was also notably enhanced due to the encapsulation of Fe 3 O 4 nanoparticles. The existing studies also reported the design and development of electrospun ternary nanofiber mats with different multifunctional performances for wound dressing applications, such as ferric oxide/gelatin/glycerol nanofiber mats [ 116 ], copper oxide nanoparticle/gelatin/PCL nanofiber mats [ 117 ], cerium oxide nanoparticle/gelatin/PCL nanofiber mats [ 118 ], sliver nanoparticle/gelatin/PVA nanofiber mats [ 119 ], tellurium nanoparticle/gelatin/PCL nanofiber mats [ 120 ], and halloysite nanotube/gelatin/PCL nanofiber mats [ 121 ].…”
Section: Electrospun Gelatin-based Nanofibersmentioning
confidence: 99%
“…Karuppannan et al added CuO nanoparticles to PCL/gel fibers using a green synthesis method. The prepared CuONF had good mechanical properties and hydrophilicity and sustained in vitro drug release for 48 h. At the same time, it had an antibacterial effect on wound pathogenic bacteria and supported the growth of fiber cells, which are effective in wound care (Karuppannan et al, 2021). Copper-Based Antibacterial Hydrogels…”
Section: Application Of Copper-based Biomaterials Copper-based Antibacterial Scaffoldsmentioning
confidence: 99%