Copper extraction: Dental consideration for Wilson's disease – An uncommon case report

Abstract

Wilson's disease is a very rare and inherited autosomal recessive disease of copper metabolism. The cause of the disease is mutation of the Adenosine triphosphate 7B (ATP7B gene). The ATP7B gene is responsible for biliary excretion of copper and incorporation of copper into ceruloplasmin. The imbalance in the copper metabolism leads to copper toxicity which primarily involves the brain, liver, the kidney, and the skeletal system. Early diagnosis and intervention is needed to prevent the mortality and morbidity of the disease. In this article, we focus on the evaluation and dental management of patients with Wilson's disease.

Multiple dens invaginatus in Wilson’s disease: A case report

“…Only a limited number of studies in the literature have explored dental procedures applied to patients with WD. Pandyan et al (26) performed tooth extraction from patients with WD under strict aseptic conditions, and no complications were reported. Authors have suggested that dentists should minimise using dental materials and medicines that contain copper (26).…”