Copper (Cu) an Essential Redox-Active Transition Metal in Living System—A Review Article

Mustafa, Syed Khalid; AlSharif, Meshari Ahmed

doi:10.4236/ajac.2018.91002

Cited by 36 publications

(18 citation statements)

References 57 publications

(1 reference statement)

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“…Copper and zinc are important trace elements which play vital roles in the body during metabolisms. They serve as cofactors to a number of key metabolic enzymes ( Mustafa and AlSharif, 2018 ; Uauy et al., 1998 ). Also, they play important roles in normal growth and development during pregnancy, childhood and adolescence.…”

Section: Resultsmentioning

confidence: 99%

Chemical and nutritional composition of some selected lesser known legumes indigenous to Nigeria

James

Nwabueze

Onwuka

et al. 2020

Heliyon

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This study evaluated the nutritional composition of Nigeria's lesser known legumes namely African breadfruit (Treculia africana), African yam bean (Sphenostylis stenocarpa) seed, bambaranut (Vigna subterranean L.), red bean (Phaseolus vulgaris), groundnut (Arachis hypogea L.), African oil bean (Pentaclethra mycrophylla Benth.) seed, cowpea (Vigna unguiculata (L.) Walp) and pigeon pea (Cajanus cajan). The proximate composition, mineral content, fibre profile, fatty acid profile and amino acid compositions were evaluated using standard methods. The results showed that legume samples vary significantly (p < 0.05) in the chemical parameters evaluated. Groundnut, African oil bean seed and African breadfruit had significantly higher protein, carbohydrate, fat and ash contents than other legumes. Equally, groundnut, African oil bean and African breadfruit showed superiority in mineral and fibre abundance, while bambaranut had the lowest mineral and fibre contents. Linolenic acid is the most abundant fatty acid in all the legumes with values ranging from 38.78-84.57%. The percentage polyunsaturated fatty acid (PUFA) for all the samples ranged from 40.15-48.97%. The total essential amino acids ranged from 24.11-66.67 mg/100 g. The range is considered adequate for ideal protein food. Therefore, lesser legumes evaluated can serve as alternative protein sources with good minerals, fibre, essential fatty and amino acids contents.

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Section: Resultsmentioning

confidence: 99%

Chemical and nutritional composition of some selected lesser known legumes indigenous to Nigeria

James

Nwabueze

Onwuka

et al. 2020

Heliyon

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“…Cu acts as an important micronutrient which increase the distribution of carbohydrate and protein metabolism and further helps to enhance the plant growth and developmental processes (Sağlam et al 2016). Cu is an important redox-active transition metal, its deficiency causes chlorosis followed by necrosis, leaf deformation, and affects reproductive organ (Mustafa and AlSharif 2018). It is the crucial transition metal but when present in excess causes toxicity, where free Cu in excess causes ROS accumulation in plant cell which damages the membrane and further halts the plant growth (Brewer 2010;Li et al 2018;Shin et al 2012).…”

Section: Copper In Plant Growth and Developmentmentioning

confidence: 99%

“…Furthermore, it serves as an important metal in promoting antioxidant machinery (Li et al 2018;Sağlam et al 2016). Cu is also required in micro amount, and higher amount further causes toxicity in plants (Mustafa and AlSharif 2018). Zn is not present in several oxidation states, therefore, does not participate in oxidoreduction reactions (Pilon et al 2009).…”

Section: Introductionmentioning

confidence: 99%

Transition Metal Homeostasis and Its Role in Plant Growth and Development

Arif

Singh

Siddiqui

et al. 2021

Microbial Biofertilizers and Micronutrient Availability

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The transition metals (Fe, Zn, Cu, and Mn) which are also considered as the micronutrient are essential for plants as they regulate various cellular metabolic activities that promote proper plant growth and development. These transition metals are also involved in photosynthesis, respiration, chlorophyll synthesis, transcription, translation, cell division, and cell elongation. However, their deficiencies and toxicity may hamper the plant growth and metabolism. Therefore, to avoid their toxicity, storage and distribution of metals in several cellular compartments are highly regulated for proper plant metabolism and growth. Alteration in metal composition of cellular organelles impairs many crucial metabolic processes of plant and further affects plant growth and yield trait. Therefore, transition metal homeostasis and cellular compartmentalization are the important processes for proper plant metabolism. This chapter highlights the transition metal homeostasis in several organelles like chloroplast, mitochondria, vacuole, vesicles, and Golgi bodies, and also covers the involvement of transporters and proteins in compartmentalization and maintaining homeostasis for proper developed biofortified crop. This chapter also includes the role of transition metals (Fe, Zn, Cu, and Mn) in plant growth and development which will help us to assess their role for sustainable agriculture and crop improvement.

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“…Particularly, Copper appears to be responsive to elevated zinc intake. Zinc ingestion of 0.05 g per day influence the copper indexes status, for instance, Cu and Zn-superoxide dismutase in erythrocytes [67][68][69] . Poor copper levels as well as ceruloplasmin levels and anemia being witnessed a higher limit of zinc ingestion, 0.45 g per day to 0.66 g per day 70,71 .…”

Section: Upper Limits Of Zinc Intakementioning

confidence: 99%

COVID-19 and Immune Function – “A Significant” Zinc

et al. 2020

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The pandemic COVID-19 is the most terrible calamity of the present human history also it has led to the worldwide issue of public health as a primary health safety problem. It was assumed that the infection of COVID -19 has two-phases, the immune protective as well as damaging phase. In the immune protective phase, clinicians try to enhance the patient immune response, and in the immune damaging phase, clinicians try to control the inflammatory immune response. Zinc belongs to the d-block or a transition element, it is an indispensable trace metal needed for vital cell activities like growth, as well as cell survival. It has significant contributions to immune homeostasis and functions; zinc inadequacy reduces primary and secondary immune responses equally. Studies have shown people who are deficient in zinc are more susceptible to infection. An inclusive knowledge of the bioavailability of the transition metal Zinc will help to be aware of those that are valuable and protective for the population's health. This work is concentrated on the significance of Zinc for the immune function, the presence of it’s in optimum amounts, and how it is beneficial to health in general and in fighting with COVID 19 in particular until today.

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Copper (Cu) an Essential Redox-Active Transition Metal in Living System—A Review Article

Cited by 36 publications

References 57 publications

Chemical and nutritional composition of some selected lesser known legumes indigenous to Nigeria

Chemical and nutritional composition of some selected lesser known legumes indigenous to Nigeria

Transition Metal Homeostasis and Its Role in Plant Growth and Development

COVID-19 and Immune Function – “A Significant” Zinc

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