Copper-catalyzed Stereoselective Synthesis of Vinyl Selenides under Ligand-free Conditions

Abstract

A mild and efficient protocol for the stereoselective synthesis of vinyl selenides catalyzed by CuO nanoparticles as recyclable catalyst under ligand-free conditions is reported. This methodology results in the synthesis of a variety of vinyl selenides in excellent yields with retention of stereochemistry.

Unexpected C−Se Cross-Coupling Reaction: Copper Oxide Catalyzed Synthesis of Symmetrical Diaryl Selenides via Cascade Reaction of Selenourea with Aryl Halides/Boronic Acids

“…In continuation of our interest in the field of cross-coupling reactions, we report herein the CuO nanoparticle-catalyzed unexpected reaction pattern of selenourea and aryl halides forming symmetrical diphenyl selenides under ligand-free conditions (Scheme ). However, to the best of our knowledge, this is the first report on the synthesis of symmetrical diphenyl selenides in the absence of any ligand or cometal catalyst.…”