Copper‐Catalyzed Decarboxylative Reductive Sulfonylation of α‐Oxocarboxylic Acids with Aryl Sulfonyl Hydrazines

Abstract

A novel and facile synthesis of aryl benzyl sulfones was accomplished for the first time through copper-catalyzed decarboxylative reductive sulfonylation reaction between α-oxocarboxylic acids and aryl sulfonyl hydrazines. The protocol proceeds smoothly under simple conditions, and has the advantages of simple operation, high yields and good functional group compatibility. This approach realizes a conceptually novel methodology for aryl benzyl sulfone synthesis under a decarboxylative reductive progress.