Copper-Bearing Metal-Organic Framework with Mucus-Penetrating Function for the Multi-Effective Clearance of Mucosal Colonized
Helicobacter pylori
Chunxi Shu,
Wei Zhang,
Yiwei Zhang
et al.
Abstract:Helicobacter pylori
colonizes over 50% of people worldwide. Biofilm formation through penetrating gastric mucus and resistance acquired by
H. pylori
markedly reduces the efficacy of traditional antibiotics. The present triple therapy and bismuth-based quadruple therapy inevitably causes intestinal flora disturbance and fails to address the excessive
H. pylori
-triggered inflammatory response. Herein, a mucus-permeable therapeutic platform (Cu-MOF@NF) … Show more
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