Coplanar PCBs and the relative contribution of coplanar PCBs, PCDDs, and PCDFs to the total 2,3,7,8-TCDD toxicity equivalents in human serum

Associations of diet with body burden of dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (PCBs): Observations on pregnant women from central Taiwan

“…This is consistent with findings from our previous studies demonstrating that maternal age is positively related to PCDD/F and PCB TEQ levels in breast milk (Chao et al 2003(Chao et al , 2004(Chao et al , 2005. Other investigators have also shown that organic pollutant body burden increases with age (Vartiainen et al 1998;Chen et al 2003), and that age is a significant predictor of levels in adults (Stark et al 1986;Kang et al 1997). Other demographic factors *Data expressed as mean WHO-TEQ levels (pg-WHO-TEQ g À1 lipid) of dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) and dioxin-like polychlorinated biphenyls (PCBs) (mean (SD)).…”

Estimating perchlorate exposure from food and tap water based on US biomonitoring and occurrence data

“…Observed differences between people may also be due to longer periods of accumulation of these persistent chemicals. Several studies have shown that levels of the more highly chlorinated dioxins, furans, and PCBs in serum or fat will increase with the age of the population studied (Falk et al, 1999;Geyer et al, 2002;Kang et al, 1997;Luotamo et al, 1991;Patterson et al, 1986). Many of the dioxins, furans and PCBs measured in a representative New Zealand population pooled sampling showed an increasing trend with age .…”

“…The sum of all congener TEQs in a specimen (total TEQ) can be used to compare dioxin-like activity among specimens. Many of the dioxin-like PCBs have lower potency but are found at higher concentrations than TCDD (Kang et al, 1997;, Van den Berg et al, 2006, so these less potent chemicals may still contribute substantially to the total TEQ.…”

Pollutant Diseases, Remediation and Recycling

“…The dioxins and furans are thus, converted to an equipotent concentration of TCDD; the product is commonly referred to as a "TCDD equivalent." Although coplanar -PCBs have less potency than dioxins and furans, their concentrations can often exceed those of TCDD such that their contribution to total TEQ is significant (Kang et al 1997;Patterson et al 1994;Kulkarni et al 2008). So far, only 7 of the 75 different dioxins, 10 of the 135 furans and 12 of the 209 PCBs have been reported to exhibit dioxin-like toxicity and were rated TEFs.…”