COP1 plays a prominent role in drought stress tolerance in Arabidopsis and Pea

Moazzam-Jazi, Maryam; Ghasemi, Samaneh; Seyedi, Seyed Mahdi; Niknam, Vahid

doi:10.1016/j.plaphy.2018.08.015

Cited by 18 publications

(14 citation statements)

References 79 publications

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“…Nevertheless, ABA greatly increases the association of COP1 with these two substrates, and enhances the ubiquitination of ABI1 and AHG3 by COP1, linking it to the stress response. Indeed, previous studies have shown that the expression of COP1 is induced by multiple stresses, including drought, salt and cold (Moazzam‐Jazi et al ., 2018). The increased COP1 levels in response to stress could incite increased COP1‐mediated degradation of some of the clade A PP2Cs promoting stomatal closure.…”

Section: Discussionmentioning

confidence: 99%

COP1 promotes ABA‐induced stomatal closure by modulating the abundance of ABI/HAB and AHG3 phosphatases

et al. 2020

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 Plant stomata are crucial to control water transpiration in response to environmental stresses and to modulate gas exchange necessary for photosynthesis. The phytohormone ABA promotes stomatal closure and inhibits light-induced stomatal opening. The Arabidopsis thaliana E3 ubiquitin ligase COP1 functions in ABA-mediated stomatal closure. However, the underlying molecular mechanisms are still not fully understood.  Yeast two-hybrid assays were used to identify ABA signaling components that interact with COP1, and biochemical, molecular and genetic studies were carried out to elucidate the regulatory role of COP1 in ABA signaling.  The cop1 mutants are hyposensitive to ABA-triggered stomatal closure under light and dark conditions. COP1 interacts with and ubiquitinates the Arabidopsis thaliana Clade A type 2C phosphatases (PP2Cs) ABI/HAB group and AHG3, thus triggering their degradation. ABA enhances the COP1-mediated degradation of these PP2Cs. Mutations in ABI1 and AHG3 partly rescue the cop1 stomatal phenotype and the phosphorylation level of OST1, a crucial Accepted Article This article is protected by copyright. All rights reserved SnRK2-type kinase in ABA signaling.  Our data indicate that COP1 is part of a novel signaling pathway promoting ABA-mediated stomatal closure by regulating the stability of a subset of the Clade A PP2Cs. These findings provide novel insights into the interplay between ABA and the light signaling component in the modulation of stomatal movement.

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Section: Discussionmentioning

confidence: 99%

COP1 promotes ABA‐induced stomatal closure by modulating the abundance of ABI/HAB and AHG3 phosphatases

et al. 2020

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“…Since the nuclear ABI4 is activated by a chloroplast-derived signal, COP1 integrates retrograde and light signaling pathways (Xu et al, 2016c). Besides acting at ABAmediated seed germination and seedling establishment, COP1 participates in ABA-induced stomatal closure and functions as an important regulator of abiotic stress responses in Arabidopsis and pea (Moazzam-Jazi et al, 2018). Recently a mechanism of COP1mediated stomatal closure via the regulation of ABA co-receptors has been described.…”

Section: The Cop1/spa Complex In Hormonal Signalingmentioning

confidence: 99%

“…Accordingly, cop1 mutants accumulate higher levels of ICE1 proteins in the nuclei of abaxial leaf epidermal cells, suggesting that the interaction partners of the COP1/SPA complex may vary according to the tissue types. In addition to stomatal differentiation, COP1 promotes ABA-mediated stomatal closure (Chen et al, 2020) and functions as an important regulator of abiotic stress in plants (Moazzam-Jazi et al, 2018). The role of COP1 in biotic stresses has also been documented.…”

Section: Other Functions Of the Cop1/spa Complexmentioning

confidence: 99%

Illuminating the COP1/SPA Ubiquitin Ligase: Fresh Insights Into Its Structure and Functions During Plant Photomorphogenesis

Ponnu

Hoecker

2021

Front. Plant Sci.

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CONSTITUTIVE PHOTOMORPHOGENIC 1 functions as an E3 ubiquitin ligase in plants and animals. Discovered originally in Arabidopsis thaliana, COP1 acts in a complex with SPA proteins as a central repressor of light-mediated responses in plants. By ubiquitinating and promoting the degradation of several substrates, COP1/SPA regulates many aspects of plant growth, development and metabolism. In contrast to plants, human COP1 acts as a crucial regulator of tumorigenesis. In this review, we discuss the recent important findings in COP1/SPA research including a brief comparison between COP1 activity in plants and humans.

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“…4d). In line with this, cop1-4 mutant leaves contained significantly high proline levels under well-watered as well as drought stress conditions (Moazzam-Jazi et al 2018). HY5 also positively regulates salt-induced transcriptional memory by maintaining H3K4me3 levels near the P5CS1 transcription start site associated with light exposure in repeated salt stresses (Feng et al 2016).…”

Section: Stress Responsementioning

confidence: 62%

HY5-COP1: the central module of light signaling pathway

Bhatnagar

Singh

Khurana

et al. 2020

J. Plant Biochem. Biotechnol.

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Light acts catalytically to initiate a cascade of events to eventually regulate different aspects of plant development. The cascade of light signal transduction involves several components that can be broadly grouped as photoreceptors, early signaling factors, central integrators and downstream effectors. ELONGATED HYPOCOTYL 5 (HY5), a bZIP transcription factor, is the most well characterized downstream effector in Arabidopsis, which acts as a positive regulator of photomorphogenesis. HY5 acts as a master regulator and binds to promoters of close to 4000 genes, thereby, regulating wide diversity of photomorphogenic responses. It physically interacts with CONSTITUTIVE PHOTOMORPHOGENIC 1 (COP1), a negative regulator of photomorphogenesis. HY5-COP1 interaction mediates cross-talk among multiple pathways, thereby, enhancing the phenotypic plasticity of plants. This interaction regulates not only the upstream components of light signaling pathway like photoreceptors but also regulates a number of downstream effectors and early signaling factors, which help to regulate a number of developmental processes in plants. This review highlights the key interaction between HY5 and COP1 and how it regulates seedling photomorphogenesis, shade avoidance, circadian clock, root architecture, flowering, thermomorphogenesis, hormone signaling and stress responses, in conjunction with other signaling components and transcription factors.

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COP1 plays a prominent role in drought stress tolerance in Arabidopsis and Pea

Cited by 18 publications

References 79 publications

COP1 promotes ABA‐induced stomatal closure by modulating the abundance of ABI/HAB and AHG3 phosphatases

COP1 promotes ABA‐induced stomatal closure by modulating the abundance of ABI/HAB and AHG3 phosphatases

Illuminating the COP1/SPA Ubiquitin Ligase: Fresh Insights Into Its Structure and Functions During Plant Photomorphogenesis

HY5-COP1: the central module of light signaling pathway

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